Results 1 to 10 of about 1,719,387 (268)
The European Zoological Journal, 2023 Non-mammal models are gaining popularity due to their ease of maintenance, low cost and lack of ethical restrictions. As some processes taking place in insect hemocytes are mirrored in human immunocytes, many immunological studies are now turning to the ...
J. Sobich +3 more
doaj +1 more source
Nucleocytoplasmic Communication in Healthy and Diseased Plant Tissues
Frontiers in Plant Science, 2021 The double membrane of the nuclear envelope (NE) constitutes a selective compartment barrier that separates nuclear from cytoplasmic processes. Plant viability and responses to a changing environment depend on the spatial communication between both ...
Daniel Lüdke +3 more
doaj +1 more source
Nature Communications, 2021 Effective chemotherapies against tuberculosis must kill the pathogen’s intracellular population. Here, Santucci et al. show that bacterial localisation within human macrophages impact pyrazinamide (PZA) accumulation and efficacy, and that combination ...
Pierre Santucci +5 more
doaj +1 more source
Viruses, 2023 Begomoviruses, which belong to the Geminiviridae family, are intracellular parasites transmitted by whiteflies to dicotyledonous plants thatsignificantly damage agronomically relevant crops. These nucleus-replicating DNA viruses move intracellularly from
Sâmera S. Breves +6 more
doaj +1 more source
Inhibition of biofilm formation in Mycobacterium smegmatis by Parinari curatellifolia leaf extracts
BMC Complementary and Alternative Medicine, 2017 Background Tuberculosis (TB) is a serious public health problem worldwide. Mycobacterium tuberculosis (M. tuberculosis) grows as drug tolerant pellicles. Agents that inhibit biofilm formation in M.
Benjamin Bhunu +2 more
doaj +1 more source
The secreted PAMP-induced peptide StPIP1_1 activates immune responses in potato
Scientific Reports, 2023 Treatment of potato plants with the pathogen-associated molecular pattern Pep-13 leads to the activation of more than 1200 genes. One of these, StPIP1_1, encodes a protein of 76 amino acids with sequence homology to PAMP-induced secreted peptides (PIPs ...
Linda Nietzschmann +7 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 Nitric oxide (NO) and electrophilic cyclopentenone prostaglandins (CyPG) are local mediators that modulate cellular response to oxidative stress in different pathophysiological processes. In particular, there is increasing evidence about their functional
Ángel Bago +3 more
doaj +1 more source
Conserved Curvature of RNA Polymerase I Core Promoter Beyond rRNA Genes: The Case of the Tritryps
Genomics, Proteomics & Bioinformatics, 2015 In trypanosomatids, the RNA polymerase I (RNAPI)-dependent promoters controlling the ribosomal RNA (rRNA) genes have been well identified. Although the RNAPI transcription machinery recognizes the DNA conformation instead of the DNA sequence of promoters,
Pablo Smircich +2 more
doaj +1 more source
The Trypanosomal Transferrin Receptor of Trypanosoma Brucei—A Review
Tropical Medicine and Infectious Disease, 2019 Iron is an essential element for life. Its uptake and utility requires a careful balancing with its toxic capacity, with mammals evolving a safe and bio-viable means of its transport and storage. This transport and storage is also utilized as part of the
Christopher K. Kariuki +2 more
doaj +1 more source
Macrophages, PPARs, and Cancer
PPAR Research, 2008 Mononuclear phagocytes often function as control switches of the immune system, securing the balance between pro- and anti-inflammatory reactions. For this purpose and depending on the activating stimuli, these cells can develop into different subsets ...
Jo A. Van Ginderachter +3 more
doaj +1 more source