Results 171 to 180 of about 155,803 (258)

Experimentally Validated Design Principles of D‐Block Transition Metal Single‐Atom Non‐Dissociative Chemisorption Solid‐State Hydrogen Storage Materials

Advanced Functional Materials, EarlyView.
A novel descriptor and a bottom‐up design principle are established to enable the rational design of hydrogen storage materials based on d‐block transition metal single‐atom COFs. By modulating H₂ adsorption through d‐orbital tuning, this approach achieves both high storage capacity and fast kinetics, while revealing a volcano‐type relationship between
Qiuyan Yue, Chao Li, Yong Gao, Zhenglong Li, Wen‐Gang Cui, Xinqiang Wang, Guoquan Na, Xiaowei Wang, Yiyang Wan, Mingchang Zhang, Yanxia Liu, Fulai Qi, Chenchen Li, Xu Xue, Jian Miao, Jing Zhang, Xiao Han, Pan Wang, Chang Guo, Xiacui Liu, Mingxia Gao, Wenping Sun, Jian Chen, Zhenhai Xia, Hongge Pan   +24 more
wiley   +1 more source

Gene Mosaicism Screening Using Single-Molecule Molecular Inversion Probes in Routine Diagnostics for Systemic Autoinflammatory Diseases

, 2019
Benjamin Kant, Ellen C. Carbo, Iris Kokmeijer, Jelske J.M. Oosterman, Joost Frenkel, Morris A. Swertz, Johannes Kristian Ploos van Amstel, Juan I. Aróstegui, Marco J. Koudijs, Mariëlle van Gijn   +9 more
openalex   +1 more source

Polymer‐Incorporated Mechanically Compliant Carbon Nanotube Microelectrode Arrays for Multichannel Neural Signal Recording

Advanced Functional Materials, EarlyView.
This work presents a soft microelectrode array based on vertically aligned carbon nanotube (CNT) forests, combining high conductivity with mechanical softness. A densification process and air‐pressure‐assisted flexibilization improve structural integrity, ensuring stable insertion and reduced inflammation.
Hyeonhee Roh, Kwangjun Kim, Chaesung Kim, Minju Kim, Minwook Kim, Sangjun Sim, Jongbaeg Kim, Jong G. Ok, Maesoon Im   +8 more
wiley   +1 more source

“Therapies Through Gut:” Targeted Drug Delivery for Non‐Gastrointestinal Diseases by Oral Administration

Advanced Healthcare Materials, EarlyView.
Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray, Shehzahdi S. Moonshi, Hang Thu Ta   +2 more
wiley   +1 more source

Lipid Nanoparticle‐Mediated CRISPR‐Cas13a Delivery for the Control of Bacterial Infection

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
New formulations of lipid nanoparticles (LNPs) that can deliver nucleic acids to Gram‐negative bacteria are proposed to combat bacterial infection. The delivery of nucleic acids by LNPs is aided by LNP‐helpers which weaken the bacterial outer membrane. LNPs encapsulating the Cas13a/gRNA expression vector achieve an antibacterial effect in both in vivo ...
Bookun Kim, Hwi Won Seo, Kyuri Lee, Dongeun Yong, Yoon Kyung Park, Yujin Lee, Solip Lee, Do‐Wan Kim, Dajeong Kim, Choong‐Min Ryu   +9 more
wiley   +1 more source

Pitfalls in the evaluation of CDKN2A copy number status in meningioma. [PDF]

J Neurooncol
Zschernack V, Pinto G, Friker LL, Klein R, Goschzik T, Dörner E, Waha A, Vokuhl C, Vatter H, Pietsch T.   +9 more
europepmc   +1 more source

Novel Less Toxic, Lymphoid Tissue‐Targeted Lipid Nanoparticles Containing a Vitamin B5‐Derived Ionizable Lipid for mRNA Vaccine Delivery

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
The top‐performing lipid nanoparticle, incorporating a novel ionizable lipid derived from vitamin B5, demonstrates high mRNA transfection efficiency, low toxicity, favorable stability, targeted delivery to lymphoid tissues, and high immunogenicity, showing promise as a carrier for mRNA vaccines for infectious diseases and cancer.
Soyeon Yoo, Muhammad Faisal, Seo‐Hyeon Bae, Kounghwa Youn, Hyo‐Jung Park, Sung Pil Kwon, Il Kwon Hwang, Jisun Lee, Hyeong Jun Kim, Jae‐Hwan Nam, Gyochang Keum, Eun‐Kyoung Bang   +11 more
wiley   +1 more source

Effect of Ultrasound on Dissolution of Polymeric Blends and Phase Inversion in Flat Sheet and Hollow Fiber Membranes for Ultrafiltration Applications. [PDF]

Membranes (Basel)
Méndez-Valdivia GK, Ballinas-Casarrubias ML, González-Sánchez G, Valdés H, Montalvo-González E, Chacón-López MA, Martínez-Montaño E, Torrestiana-Sánchez B, Miramontes-Escobar HA, Ortiz-Basurto RI.   +9 more
europepmc   +1 more source

Bioengineering a Patient‐Derived Vascularized Lung Tumor‐on‐Chip Model to Decipher Immunomodulation by the Endothelium

Advanced Healthcare Materials, EarlyView.
Most in vitro cancer models lack cellular diversity, functional complexity, and clinical relevance. This work highlights the generation of an innovative dynamic tetraculture with autologous patient‐derived cells within a vascularized tumor‐on‐chip, as well as the recapitulation of endothelial anergy features induced by the tumor microenvironment ...
Christine Lansche, Ségolène Ladaigue, Giacomo Gropplero, Nicolas Zimmermann, Martin Nurmik, Irina Veith, Manh‐Louis Nguyen, Solenn Brosseau, Nicolas Poté, Pierre Mordant, Arnaud Roussel, Fathia Mami‐Chouaib, Fatima Mechta‐Grigoriou, Gérard Zalcman, Fabrice Soncin, Stéphanie Descroix, Maria Carla Parrini   +16 more
wiley   +1 more source

Epigenetic state and gene expression remain stable after CRISPR/Cas-mediated chromosomal inversions. [PDF]

New Phytol
Khosravi S, Hinrichs R, Rönspies M, Haghi R, Puchta H, Houben A.   +5 more
europepmc   +1 more source