Results 11 to 20 of about 206,828 (101)

Genome-wide copy number aberrations and HER2 and FGFR1 alterations in primary breast cancer by molecular inversion probe microarray

OncoTarget, 2017
Breast cancer remains the second leading cause of cancer-related death in women despite stratification based on standard hormonal receptor (HR) and HER2 testing. Additional prognostic markers are needed to improve breast cancer treatment. Chromothripsis,
Hui Chen, Rajesh R. Singh, Xinyan Lu, Lei Huo, Hui Yao, Kenneth Aldape, Ronald Abraham, Shumaila Virani, Meenakshi Mehrotra, Bal M. Mishra, Alex Bousamra, Constance T. Albarracin, Yun Wu, Sinchita Roy‐Chowdhuri, Rashmi Kanagal‐Shamanna, Mark J. Routbort, L. Jeffrey Medeiros, Keyur P. Patel, Russell R. Broaddus, Ayşegül A. Şahin, Rajyalakshmi Luthra   +20 more
openalex   +3 more sources

Investigating Single-Molecule Molecular Inversion Probes for Medium-Scale Targeted DNA Methylation Analysis

Epigenomes
Background: Epigenetic biomarkers, particularly CpG methylation, are increasingly employed in clinical and forensic settings. However, we still lack a cost-effective, sensitive, medium-scale method for the analysis of hundreds to thousands of user ...
Roy B. Simons, Hieab H.H. Adams, Manfred Kayser, Athina Vidaki   +3 more
openalex   +2 more sources

Comprehensive Screening of Gene Copy Number Aberrations in Formalin-Fixed, Paraffin-Embedded Solid Tumors Using Molecular Inversion Probe–Based Single-Nucleotide Polymorphism Array [PDF]

Journal of Molecular Diagnostics, 2016
Rajesh R. Singh, Meenakshi Mehrotra, Hui Chen, Alaa A. Almohammedsalim, Ayesagul Sahin, Alex Bosamra, Keyur P. Patel, Mark J. Routbort, Xinyan Lu, Ronald Abraham, Bal M. Mishra, Shumaila Virani, L. Jeffrey Medeiros, Rajyalakshmi Luthra   +13 more
openalex   +2 more sources

High quality copy number and genotype data from FFPE samples using Molecular Inversion Probe (MIP) microarrays [PDF]

BMC Medical Genomics, 2009
BackgroundA major challenge facing DNA copy number (CN) studies of tumors is that most banked samples with extensive clinical follow-up information are Formalin-Fixed Paraffin Embedded (FFPE). DNA from FFPE samples generally underperforms or suffers high
Yuker Wang, Victoria Carlton, George Karlin‐Neumann, Ronald J. Sapolsky, Li Zhang, Martin Moorhead, Zhigang C. Wang, Andrea L. Richardson, Robert S. Warren, Axel Walther, Melissa L. Bondy, Aysegul Sahin, Ralf Krahe, Musaffe Tuna, Patricia A. Thompson, Paul T. Spellman, Joe W. Gray, Gordon B. Mills, Malek Faham   +18 more
openalex   +2 more sources

Bayesian Hierarchical Structured Variable Selection Methods with Application to Molecular Inversion Probe Studies in Breast Cancer [PDF]

, 2014
Lin Zhang, Veerabhadran Baladandayuthapani, Bani K. Mallick, Ganiraju C. Manyam, Patricia A. Thompson, Melissa L. Bondy, Kim‐Anh Do   +6 more
openalex   +2 more sources

Highly multiplex molecular inversion probe panel in Plasmodium falciparum targeting common SNPs approximates whole genome sequencing assessments for selection and relatedness

medRxiv
Karamoko Niaré, Rebecca Crudale, Abebe A. Fola, Neeva Wernsman Young, Victor Asua, Melissa D. Conrad, Pierre Gashema, Anita Ghansah, Stan Hangi, Deus S. Ishengoma, Jean-Baptiste Mazarati, Ayalew Jejaw Zeleke, Philip Rosenthal, Abdoulaye Djimdé, Jonathan J. Juliano, Jeffrey A. Bailey   +15 more
openalex   +2 more sources

Molecular inversion probe analysis detects novel copy number alterations in Ewing sarcoma [PDF]

Cancer Genetics, 2012
Mona S. Jahromi, Angelica R. Putnam, Colleen Druzgal, Jennifer Wright, Holly Spraker‐Perlman, Michelle Kinsey, Holly Zhou, Kenneth M. Boucher, R. Lor Randall, Kevin B. Jones, David R. Lucas, Andrew E. Rosenberg, Dafydd G. Thomas, Stephen L. Lessnick, Joshua D. Schiffman   +14 more
openalex   +2 more sources

Molecular Inversion Probe Analysis of Gene Copy Alterations Reveals Distinct Categories of Colorectal Carcinoma [PDF]

Cancer Research, 2006
Hanlee P. Ji, Jochen Kumm, Michael Zhang, Kyle Farnam, Keyan Salari, Malek Faham, James M. Ford, Ronald W. Davis   +7 more
openalex   +2 more sources

An improved molecular inversion probe based targeted sequencing approach for low variant allele frequency

NAR Genomics and Bioinformatics, 2022
Deep targeted sequencing technologies are still not widely used in clinical practice due to the complexity of the methods and their cost. The Molecular Inversion Probes (MIP) technology is cost effective and scalable in the number of targets, however ...
Tamir Biezuner, Yardena Brilon, Asaf Ben Arye, Barak Oron, Aditee Kadam, A. Danin, N. Furer, M. Minden, Dennis Dong Hwan Kim, S. Shapira, N. Arber, J. Dick, P. Thavendiranathan, Y. Moskovitz, N. Kaushansky, N. Chapal-Ilani, L. Shlush   +16 more
semanticscholar   +1 more source

Molecular Inversion Probe-Based Sequencing of USH2A Exons and Splice Sites as a Cost-Effective Screening Tool in USH2 and arRP Cases

International Journal of Molecular Sciences, 2021
A substantial proportion of subjects with autosomal recessive retinitis pigmentosa (arRP) or Usher syndrome type II (USH2) lacks a genetic diagnosis due to incomplete USH2A screening in the early days of genetic testing.
Janine Reurink, A. Dockery, D. Oziębło, G. Farrar, M. Ołdak, J. T. ten Brink, A. Bergen, T. Rinne, H. Yntema, R. Pennings, L. I. van den Born, Marco Aben, J. Oostrik, H. Venselaar, A. Plomp, M. I. Khan, E. van Wijk, F. Cremers, S. Roosing, H. Kremer   +19 more
semanticscholar   +1 more source