Results 51 to 60 of about 353,887 (261)

Clonal hematopoiesis in the donor does not adversely affect long-term outcomes following allogeneic hematopoietic stem cell transplantation: result from a 13-year follow-up

Haematologica, 2023
Donor clonal hematopoiesis may be transferred to the recipient through allogeneic hematopoietic stem cell transplantation (HSCT), but the potential for adverse long-term impact on transplant outcomes remains unknown.
Kyoung Ha Kim, TaeHyung Kim, Igor Novitzky-Basso, Hyewon Lee, Youngseok Yoo, Jae-Sook Ahn, Ivan Pasic, Arjun Law, Wilson Lam, Fotios V. Michelis, Armin Gerbitz, Auro Viswabandya, Jeffrey Lipton, Rajat Kumar, Jonas Mattsson, Zhaolei Zhang, Nathali Kaushansky, Yardena Brilon, Noa Chapal-Ilani, Tamir Biezuner, Liran I Shlush, Dennis Dong Hwan Kim   +21 more
doaj   +1 more source

Inverting pump-probe spectroscopy for state tomography of excitonic systems [PDF]

J. Chem. Phys. 138, 164102 (2013), 2012
We propose a two-step protocol for inverting ultrafast spectroscopy experiments on a molecular aggregate to extract the time-evolution of the excited state density matrix. The first step is a deconvolution of the experimental signal to determine a pump-dependent response function.
arxiv   +1 more source

Probing rotational wave-packet dynamics with the structural minimum in high-order harmonic spectra [PDF]

Optics Express, Vol. 22, Issue 6, pp. 6362-6371 (2014), 2014
We investigate the alignment-dependent high-order harmonic spectrum generated from nonadiabatically aligned molecules around the first half rotational revival. It is found that the evolution of the molecular alignment is encoded in the structural minima. To reveal the relation between the molecular alignment and the structural minimum in the high-order
arxiv   +1 more source

Copy number analysis by low coverage whole genome sequencing using ultra low-input DNA from formalin-fixed paraffin embedded tumor tissue

Genome Medicine, 2016
Unlocking clinically translatable genomic information, including copy number alterations (CNA), from formalin-fixed paraffin-embedded (FFPE) tissue is challenging due to low yields and degraded DNA. We describe a robust, cost-effective low-coverage whole
Tanjina Kader, David L. Goode, Stephen Q. Wong, Jacquie Connaughton, Simone M. Rowley, Lisa Devereux, David Byrne, Stephen B. Fox, Gisela Mir Arnau, Richard W. Tothill, Ian G. Campbell, Kylie L. Gorringe   +11 more
doaj   +1 more source

HemoMIPs-Automated analysis and result reporting pipeline for targeted sequencing data.

PLoS Computational Biology, 2020
Targeted sequencing of genomic regions is a cost- and time-efficient approach for screening patient cohorts. We present a fast and efficient workflow to analyze highly imbalanced, targeted next-generation sequencing data generated using molecular ...
Philip Kleinert, Beth Martin, Martin Kircher   +2 more
doaj   +1 more source

Highly multiplexed targeted sequencing strategy for infectious disease surveillance

BMC Biotechnology, 2023
Background Global efforts to characterize diseases of poverty are hampered by lack of affordable and comprehensive detection platforms, resulting in suboptimal allocation of health care resources and inefficient disease control.
Iván Hernández-Neuta, Anastasia Magoulopoulou, Flor Pineiro, Jan Gorm Lisby, Mats Gulberg, Mats Nilsson   +5 more
doaj   +1 more source

Comparison of three targeted enrichment strategies on the SOLiD sequencing platform. [PDF]

PLoS ONE, 2011
Despite the ever-increasing throughput and steadily decreasing cost of next generation sequencing (NGS), whole genome sequencing of humans is still not a viable option for the majority of genetics laboratories.
Dale J Hedges, Toumy Guettouche, Shan Yang, Guney Bademci, Ashley Diaz, Ashley Andersen, William F Hulme, Sara Linker, Arpit Mehta, Yvonne J K Edwards, Gary W Beecham, Eden R Martin, Margaret A Pericak-Vance, Stephan Zuchner, Jeffery M Vance, John R Gilbert   +15 more
doaj   +1 more source

Novel molecular aberrations and pathologic findings in a tubulocystic variant of renal cell carcinoma

Indian Journal of Pathology and Microbiology, 2013
Tubulocystic renal cell carcinoma (TRCC) is an indolent type of renal cell carcinoma with a good prognosis based on the limited number of published cases. Herein, we describe the unusual clinical, pathologic and molecular findings in a case of TRCC.
Nikhil A Sangle, Rong Mao, Shashirekha Shetty, Joshua D Schiffman, Christopher Dechet, Lester Layfield, Neeraj Agarwal, Ting Liu   +7 more
doaj   +1 more source

Loss of expression and promoter methylation of SLIT2 are associated with sessile serrated adenoma formation. [PDF]

PLoS Genetics, 2013
Serrated adenomas form a distinct subtype of colorectal pre-malignant lesions that may progress to malignancy along a different molecular pathway than the conventional adenoma-carcinoma pathway.
Andrew D Beggs, Angela Jones, Neil Shepherd, Abed Arnaout, Caroline Finlayson, A Muti Abulafi, Dion G Morton, Glenn M Matthews, Shirley V Hodgson, Ian P M Tomlinson   +9 more
doaj   +1 more source

Recurrent loss of heterozygosity in 1p36 associated with TNFRSF14 mutations in IRF4 translocation negative pediatric follicular lymphomas

Haematologica, 2013
Pediatric follicular lymphoma is a rare disease that differs genetically and clinically from its adult counterpart. With the exception of pediatric follicular lymphoma with IRF4-translocation, the genetic events associated with these lymphomas have not ...
Idoia Martin-Guerrero, Itziar Salaverria, Birgit Burkhardt, Monika Szczepanowski, Michael Baudis, Susanne Bens, Laurence de Leval, Africa Garcia-Orad, Heike Horn, Jasmin Lisfeld, Shoji Pellissery, Wolfram Klapper, Ilske Oschlies, Reiner Siebert   +13 more
doaj   +1 more source