Results 81 to 90 of about 5,075,651 (313)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Mount Liebig, Northern Territory [cartographic material] : Commonwealth topographic survey /

open access: yes, 1960
Provisional ed. Topographic map of Mount Liebig region, Northern Territory, showing classes of roads, railway and telephone lines, mines, post offices, wireless transceivers, windpumps, airports or airfields and landing grounds, horizontal control points,
Australia. Division of National Mapping.
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Alice Springs, Northern Territory [cartographic material] : Commonwealth topographic survey /

open access: yes, 1959
Provisional ed. Topographic map of Alice Springs region, Northern Territory, showing classes of roads, railway and telephone lines, mines, post offices, wireless transceivers, windpumps, airports or airfields and landing grounds, horizontal control ...
Australia. Division of National Mapping.
core  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Photo index ... New Guinea [cartographic material].

open access: yes, 1956
Photomosaic series of Papua New Guinea.; "This photo index is merely a copy of an assembly of air photographs and is not an accurate map."; "Names shown in red on this map have been supplied by C.S.I.R.O. Land Research Unit and are subject to approval by
Australia. Division of National Mapping.
core  

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Molecular maps of myosin.

open access: yesSeibutsu Butsuri, 1988
Three functionally important sites of myosin head, i.e. ATPase site, actin-binding site and SH1 thiol, were identified in its three-dimensional structure by electron microscopy. These sites were also mapped along primary structures of myosin heavy and light chains by chemical methods such as affinity labeling, chemical crosslinking and "end-label ...
openaire   +2 more sources

Cape Scott, Northern Territory [cartographic material] : Commonwealth topographic survey /

open access: yes, 1960
Provisional ed. Topographic map of Cape Scott region, Northern Territory showing classes of roads, railway and telephone lines, mines, post offices, wireless transceivers, windpumps, airports or airfields and landing grounds, horizontal control points ...
Australia. Division of National Mapping.
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

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