Results 101 to 110 of about 1,944,612 (362)

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

FEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile, Daniela Ratto, Giorgia Rastelli, Ottavia Eleonora Ferraro, Caterina Temporini, Sunil Kumar, Simona Boncompagni, Paola Rossi, Monica Canepari   +8 more
wiley   +1 more source

Molecular Marker Linkage Map for Apple [PDF]

, 2017
Linkage maps for two apple clones, White Angel and Rome Beauty, were constructed using isozyme and DNA polymorphisms segregating in a population produced from a Rome Beauty × White Angel cross.
Hemmat, M., Lawson, D. M., Manganaris, A. G., Weedon, N. F.   +3 more
core  

Molecular breeding for resilience in maize - A review [PDF]

, 2015
Abiotic and biotic constraints have widespread yield reducing effects on maize and should receive high priority for maize breeding research. Molecular Breeding offers opportunities for plant breeders to develop cultivars with resilience to such diseases ...
Abidi, I., Ali, G., Dar, Z. A., Gazal, Asima, Lone, A. A.   +4 more
core   +2 more sources

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Low Cost DNA Molecular Weight Marker: Primer-Directed Synthesis from pGEM-T Easy Vector

Walailak Journal of Science and Technology, 2011
A low cost DNA molecular weight marker was produced by a marker primer-directed synthetic method using pGEM-T Easy vector as the DNA template. Seven primers were used to amplify eight different DNA fragments, which were 150, 300, 375, 500, 700, 1,000, 1 ...
Siriporn RIYAJAN, Wiparat YENTUA, Jaros PHINCHONGSAKULDIT   +2 more
doaj   +1 more source

Divergent Effects of Metformin on an Inflammatory Model of Parkinson’s Disease [PDF]

, 2018
The oral antidiabetic drug metformin is known to exhibit anti-inflammatory properties through activation of AMP kinase, thus protecting various brain tissues as cortical neurons, for example. However, the effect of metformin on the substantia nigra (SN),
Boza-Serrano, Antonio,, de Pablos, Rocío M.,, Deierborg, Tomas,, Espinosa-Oliva, Ana M.,, García-Domínguez, Irene,, Herrera, Antonio J.,, Ismaiel, Afrah Abdul,, Lund University., Lund University., Machado, Alberto,, Tayara, Khadija,, Venero, José L.,   +11 more
core   +1 more source

Serial amplification of tau filaments using Alzheimer's brain homogenates and C322A or C322S recombinant tau

FEBS Letters, EarlyView.
We investigated the seeded assembly of 0N3R tau and two variants, C322A and C322S, designed to model the mutation landscape at residue 322, using Alzheimer's disease brain homogenates in a real‐time quaking‐induced conversion (RT‐QuIC) assay. The C322A variant formed filaments that partially resembled the paired helical filament (PHF) structure ...
Alessia Santambrogio, Sofia Lövestam, Michael A. Metrick II, Thomas Löhr, Peifeng Xu, Nicholas C. T. Gallagher, Bernardino Ghetti, Byron Caughey, Sjors H. W. Scheres, Michele Vendruscolo   +9 more
wiley   +1 more source

Variabilidade genética de Colletotrichum guaranicola usando marcadores AFLP Variability of Colletotrichum guaranicola using AFLP markers

Acta Amazonica, 2011
Foi detectada a variabilidade genética de vinte isolados de Colletotrichum guaranicola (Albuq.) provenientes de diferentes localidades produtoras de guaraná no Amazonas, utilizando-se marcadores moleculares AFLP.
Jânia Lilia da Silva Bentes, Pedro Queiroz Costa Neto   +1 more
doaj   +1 more source

Diversity, genetic mapping, and signatures of domestication in the carrot (Daucus carota L.) genome, as revealed by Diversity Arrays Technology (DArT) markers [PDF]

, 2013
Carrot is one of the most economically important vegetables worldwide, but genetic and genomic resources supporting carrot breeding remain limited. We developed a Diversity Arrays Technology (DArT) platform for wild and cultivated carrot and used it to ...
Allender, Charlotte J., Baranski, Rafal, Cavagnaro, Pablo, Ellison, Shelby, Grzebelus, Dariusz, Heller-Uszynska, Kasia, Iorizzo, Massimo, Kilian, Andrzej, Macko-Podgorni, Alicja, Nothnagel, Thomas, Senalik, Douglas, Simon, P. W. (Philipp W.)   +11 more
core   +3 more sources

Molecular markers and their potentials

International Journal of Bioassays, 2016
The use of molecular markers, revealing polymorphism at the DNA level, has been playing an increasing part in plant molecular biotechnology and their genetic studies. There are three different types of markers viz. morphological, biochemical and DNA based molecular markers. These DNA based markers are differentiating in two types 1. Non PCR based (RFLP)
Anuprita Zore, Gayatri Wadiye, Arifa Khatoon, Sumeet Verma   +3 more
openaire   +2 more sources