Results 181 to 190 of about 1,994,871 (347)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

molecular markers

Annals of Oncology, 2006
openaire   +2 more sources

Advances and challenges in plant molecular marker technologies and their applications in the artificial intelligence empowered era. [PDF]

Front Plant Sci
Li X, Hu Z, Yu W, Xie H, Wang X, Huang P, Zhang X, Yang J, Li Y, Zhao W, Yang X, Zhang Z, Pu W, Li Z.   +13 more
europepmc   +1 more source

Molecular markers in oral lichen planus: A systematic review

, 2016
Shitalkumar Sagari, Sudhanshu Sanadhya, Mallikarjun H. Doddamani, Rajan Rajput   +3 more
openalex   +1 more source

Diagnosis of SARS-CoV-2 infection and COVID-19: accuracy of signs and symptoms; molecular, antigen, and antibody tests; and routine laboratory markers

, 2020
Jonathan J Deeks, Jacqueline Dinnes, Yemisi Takwoingi, Clare Davenport, Mariska Leeflang, René Spijker, Lotty Hooft, Ann Van den Bruel, Devy Emperador, Sabine Dittrich   +9 more
openalex   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Molecular Marker-Based Identification of Resistance to <i>Bipolaris sorokiniana</i> in Kazakh and Global Wheat Germplasm. [PDF]

Biology (Basel)
Bolatbekova A, Kokhmetova A, Dutbayev Y, Özer G, Kumarbayeva M, Bastaubayeva S, Kharipzhanova A, Nurzhuma M, Keishilov Z, Kokhmetova A, Bakhytuly K, Mukhametzhanov K, Tsygankov V.   +12 more
europepmc   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Punctual mutations in lipoxygenase sequence expressed in black soybean seed coat

Journal of Seed Science
Lipoxygenase enzymes are relevant in several characteristics of soybean seeds, such as germination performance, storage capacity and tolerance to infection by microorganisms.
Liliane Marcia Mertz, Fernando Augusto Henning, Ana Paula Piccinin Barbieri, Samantha Rigo Segalin, Francisco Carlos Krzyzanowski, Paulo Dejalma Zimmer   +5 more
doaj  

A Clinicopathology and Simplified Molecular Marker-Based Risk Stratification Model for Predicting 3-Year Recurrence in Endometrial Cancer. [PDF]

Clin Med Insights Oncol
Zhang J, Zhou Y, Huang Y, Qin X, Yang H, Yang C, Guo J.   +6 more
europepmc   +1 more source