Results 201 to 210 of about 1,994,871 (347)

Genetic diversity of Pseudomonas aeruginosa isolated from clinical samples with ISSR molecular marker in a tertiary care teaching hospital. [PDF]

Sci Rep
Mishra P, Sahoo D, Sahu MC.
europepmc   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Chloroplast Genome Analysis of Six <i>Camellia sinensis</i> Accessions: Genetic Divergence, Adaptive Evolution, and Molecular Marker Development. [PDF]

Biology (Basel)
Fu Y, Pan L, Du X, Hao Z.
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

GWAS identifies a molecular marker cluster associated with monoterpenoids in grapes. [PDF]

Hortic Res
Zhang HM, Lyu XJ, Sun ZY, Sun Q, Wang YC, Sun L, Xu HY, He L, Duan CQ, Pan QH.   +9 more
europepmc   +1 more source

Molecular characterization of gherkin genotypes using SSR markers of cucumber [PDF]

Deepika Deepika, Shivayogi Ryavalad, Rekha Chittapur, Spoorti Tirki, Raveendra S Jawadagi   +4 more
openalex   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

MYB polymorphism molecular marker: A novel molecular marker for authenticity and geographical origin identification of <i>Citri Reticulatae Pericarpium</i>. [PDF]

Chin Herb Med
Cheng Q, Tang Z, Ouyang Y, Cheng C, Lao C, Cui H, Zhou H, Liang Y.   +7 more
europepmc   +1 more source

Comparison of digital PCR platforms using the molecular marker. [PDF]

Genomics Inform, 2023
Lee CJ, Shin W, Song M, Shin SS, Park Y, Srikulnath K, Kim DH, Han K.   +7 more
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source