In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim+11 more
wiley +1 more source
Editorial: Molecular markers for pancreatic cancers: new technologies and applications in the clinical practice. [PDF]
Moyana T, Merz V.
europepmc +1 more source
072 Backcross Breeding with RAPD Molecular Markers to Enhance Resistance to Common Bacterial Blight in Pinto Beans [PDF]
Nedim Mutlu+3 more
openalex +1 more source
Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez+5 more
wiley +1 more source
MMP14 and DDR2 are potential molecular markers for metastatic triple-negative breast cancer. [PDF]
Al-Temaimi R, Ahmad R, Al-Mulla F.
europepmc +1 more source
Typing Tuber melanosporum and Chinese black truffle species by molecular markers [PDF]
Francesco Paolocci
openalex +1 more source
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima+6 more
wiley +1 more source
Five Cellular Genes as Candidates for Cervical Adenocarcinoma Molecular Markers. [PDF]
García-Montoya IA+7 more
europepmc +1 more source
Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides+13 more
wiley +1 more source
Molecular characterization of Serrasalmidae hybrid in the upper Paraná River floodplain using molecular markers. [PDF]
Ramos LI+4 more
europepmc +1 more source