Results 291 to 300 of about 7,421,514 (390)

Establishing the relationship between heavy oil viscosity and molecular markers using an enhanced neural network model. [PDF]

Sci Rep
Zhong M, Niu Z, Fan J, Huang H, Li N, Li J, Zhang H.   +6 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Five Cellular Genes as Candidates for Cervical Adenocarcinoma Molecular Markers. [PDF]

Cancers (Basel)
García-Montoya IA, López-Córdova KB, Marrero-Rodríguez D, Salcedo-Vargas M, Vargas-Requena CL, Escárcega-Avila AM, Martel-Estrada SA, Jiménez-Vega F.   +7 more
europepmc   +1 more source

Additional file 11: Supplemental dataset S9. of Genome sequencing of the staple food crop white Guinea yam enables the development of a molecular marker for sex determination

, 2017
Muluneh Tamiru, Satoshi Natsume, Hiroki Takagi, Benjamen White, Hiroki Yaegashi, Motoki Shimizu, Kentaro Yoshida, Aiko Uemura, Kaori Oikawa, Akira Abe, Naoya Urasaki, Hideo Matsumura, Pachakkil Babil, Shinşuke Yamanaka, Ryo Matsumoto, Satoru Muranaka, Gezahegn Girma, Antonio Lopez‐Montes, Melaku Gedil, Ranjana Bhattacharjee, Michael Abberton, Pradeep Kumar, Ismail Rabbi, Mai Tsujimura, Toru Terachi, Wilfried Haerty, Manuel Corpas, Sophien Kamoun, GĂźnter Kahl, H. Takagi, Robert Asiedu, Ryohei Terauchi   +31 more
openalex   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

State of the art in grapevine variety and clone identification through polymorphism in DNA molecular markers

, 2013
Claudio D’Onofrio
openalex   +2 more sources

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Genomic analyses of Purpureocillium lilacinum reveal unique DNA regions for developing isolate-specific molecular markers. [PDF]

BMC Genomics
Yeh ZY, Mushyakhwo K, Ni NT, Lo PH, Lin CF, Nai YS.   +5 more
europepmc   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Editorial: Molecular markers for pancreatic cancers: new technologies and applications in the clinical practice. [PDF]

Front Oncol
Moyana T, Merz V.
europepmc   +1 more source