Results 201 to 210 of about 4,145,178 (349)

The Protective Effect and Molecular Mechanism of Tetrandrine on Male Reproductive Damage Caused by Silicon Dioxide. [PDF]

Toxics
Li HM, Zeng XQ, Chang Q, Sheng YX, Pu YJ, Wang Y, Cheng B, Li HH, Xuan J, Zhang L, Xu HM.   +10 more
europepmc   +1 more source

Molecular mechanisms of signalling mediated by the NOD FACTOR PERCEPTION receptor in Medicago truncatula

, 2022
Thi Bich Luu
openalex   +1 more source

Enhancement of molecular polarizabilities by the push-pull mechanism; a DFT study of substituted benzene, furan, thiophene and related molecules [PDF]

, 2006
Alan Hinchliffe, Ahmed M. Mkadmh, Beatrice Nikolaidi, Humberto Soscún, Fakhr M. Abu-Awwad   +4 more
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Molecular Mechanism of MLC 901 in Acute Ischemic Stroke: A Review. [PDF]

Stroke Res Treat
Hunaifi I, Bintang AK, Tammasse J, Wahid I, Hatta M, Islam AA, Zainuddin AA, Sugianto P.   +7 more
europepmc   +1 more source

Domain cross-talk in regulation of histone modifications: Molecular mechanisms and targeting opportunities

, 2020
James E. Longbotham, Meng Yao Zhang, Danica Galonić Fujimori   +2 more
openalex   +2 more sources

Dissecting the Molecular Mechanism of 2-APB-Induced Inhibition of Stim1-Orai1 Coupling [PDF]

, 2014
Youjun Wang, Xizhuo Wang, Yandong Zhou, Eunan Hendron, Lucas Occhiena, Ming Wei, Donald L. Gill   +6 more
openalex   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Molecular mechanism of RBM15-mediated m6A modification in hepatitis B virus replication. [PDF]

Virol J
Ni M, Li B, Wang L, Ma S, Ma K.
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source