Results 231 to 240 of about 4,145,178 (349)
Life Factors and Melanoma: From the Macroscopic State to the Molecular Mechanism. [PDF]
Wang H, Zhang H, Zhou Y, Li C, Guo W.
europepmc +1 more source
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
A Mechanistic Insight into the Molecular Mechanism of the Thermal Decomposition of Nitroalkyl Phosphates: MEDT Computational Study. [PDF]
Woliński P, Dresler E, Jasiński R.
europepmc +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
<i>MTAP</i> Deletion as a Therapeutic Vulnerability in Cancer: From Molecular Mechanism to Clinical Targeting. [PDF]
Krawczyk P, Wojas-Krawczyk K.
europepmc +1 more source
Molecular mechanisms and clinical features of heart failure
Satoshi Suzuki, Yasuchika Takeishi
openalex +2 more sources

