Results 251 to 260 of about 4,145,178 (349)

The molecular mechanism of traditional Chinese medicine in the treatment of oropharyngeal candidiasis (OPC). [PDF]

J Oral Microbiol
Wang S, Wang H, Wei W, Wang T.
europepmc   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Molecular mechanism of follicular development in laying hens based on the regulation of water metabolism. [PDF]

Open Life Sci
Chen X, Lyu S, Zhou H, Zou X, Yu J, Liu Y.   +5 more
europepmc   +1 more source

Molecular mechanisms of transthyretin-induced cytotoxicity

, 2017
Xu Hou
openalex   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Exploring the Molecular Mechanism of Hepatic Dysfunction Among Workers Exposed to Nickel and Chromium in Electroplating. [PDF]

Int J Mol Sci
Ramadan MA, Abdelgwad M, Atawia RT, Badr AM, Khalifa EM, Alkharashi LA, Mohammed RS.   +6 more
europepmc   +1 more source

Functional Supramolecular Materials Based on Multiple Hydrogen-Bonding Motifs and the Associated Molecular Interaction Mechanism

, 2019
Jingsi Chen
openalex   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Global Profiling of the Proteome and Acetylome in Mice with Abdominal Aortic Aneurysms

ACS Omega
Luyao Zhang, Bo Yang, Tao Ding, Yaling Zhao, Yehong Yang, Xiaoyue Tang, Yue Wu, Qiaochu Wang, Zhiyi Zhang, Chunmei Shi, Rong Han, Xutong Zhang, Jiangfeng Liu, Juntao Yang   +13 more
doaj   +1 more source

NO/NOS system dysregulation as a key molecular mechanism in chemotherapy-induced cardiotoxicity: a review. [PDF]

Front Cardiovasc Med
Nagy A, Virág Z, Kiss V, Börzsei D, Varga C, Szabó R.   +5 more
europepmc   +1 more source