Results 281 to 290 of about 4,145,178 (349)

Molecular mechanism of Activin receptor inhibition by DLK1. [PDF]

Nat Commun
Antfolk D, Ming Q, Manturova A, Goebel EJ, Thompson TB, Luca VC.   +5 more
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Exploring the molecular mechanism of apigenin in treating bronchiectasis based on network pharmacology and molecular docking. [PDF]

Sci Rep
Huang H, Han J, Liu Y, Zhang Q, Zhou Y, Zheng S, Zhou C, Bao C, Qing C, Lu W, Wu X, Jiang Y, Zhang L, Luo J, Kong J.   +14 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Ferroptosis as a potential molecular mechanism of bipolar disorder. [PDF]

Transl Psychiatry
Yehia A, Melhuish Beaupre LM, Ho MC, Biernnacka JM, Frye MA, Abulseoud OA.   +5 more
europepmc   +1 more source

A Comprehensive Review on the Molecular Mechanism of Lycopene in Cancer Therapy. [PDF]

Food Sci Nutr
Maaz M, Sultan MT, Khalid MU, Raza H, Imran M, Hussain M, Al Abdulmonem W, Alsagaby SA, Abdelgawad MA, Ghoneim MM, Khan MA, Yehuala TF, Selim S, Mostafa EM.   +13 more
europepmc   +1 more source

Molecular mechanism of berberine in ameliorating leptin resistance and mitochondrial dysfunction through the TRIB1-C/EBPα axis in obesity. [PDF]

Chin Med
Zhang X, Zhang C, Meng X, Tang J.
europepmc   +1 more source

Structural insights into AQP3 channel closure upon pH and redox changes reveal an autoregulatory molecular mechanism. [PDF]

Nat Commun
Huang P, Venskutonytė R, Wilson CJ, Bsharat S, Prasad RB, Gourdon P, Artner I, de Groot BL, Lindkvist-Petersson K.   +8 more
europepmc   +1 more source

Deep fusion of incomplete multi-omic data for molecular mechanism of Alzheimer's disease. [PDF]

Sci Rep
Xie L, Raj Y, Tong M, Nho K, Salama P, Saykin AJ, Fang S, Yan J.   +7 more
europepmc   +1 more source

CDKL5 Deficiency Disorder: Revealing the Molecular Mechanism of Pathogenic Variants. [PDF]

Int J Mol Sci
Paul SK, Panday SK, Boccuto L, Alexov E.
europepmc   +1 more source