Results 351 to 360 of about 14,308,960 (385)

Molecular mechanisms of forgetting

European Journal of Neuroscience, 2020
AbstractThe field of learning and memory has largely focused their efforts on memory formation, deeming the act of forgetting as a necessary and unavoidable error of the brain's storage system. However, recent studies show that forgetting might be a purposeful mechanism with dedicated molecular pathways.
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Cellular and molecular mechanisms of curcumin in prevention and treatment of disease

Critical reviews in food science and nutrition, 2020
Curcumin is a naturally occurring polyphenolic compound present in rhizome of Curcuma longa belonging to the family zingiberaceae. Growing experimental evidence revealed that curcumin exhibit multitarget biological implications signifying its crucial ...
S. Patel, Ashish Acharya, R. S. Ray, R. Agrawal, R. Raghuwanshi, P. Jain   +5 more
semanticscholar   +1 more source

ChemInform Abstract: THE MOLECULAR MECHANISMS OF ANESTHESIA

Chemischer Informationsdienst, 1977
IT is generally accepted that neutral anaesthetics, such as the n-alkanols and n-alkanes, act from a hydrophobic site1. Discussion has tended to focus on the nature of this site and, particularly, whether it is located in a membrane protein or in the interior of a bilayer2,3.
D.A. Haydon, S R Levinson, S R Levinson, Bruce M. Hendry, J Requena   +4 more
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Molecular mechanisms of pathogenesis

Clinics in Dermatology, 1983
Abstract The first clue to the etiology of pemphigus was established in 1964, when Beutner and Jordon 1 demonstrated that serum from pemphigus patients contained autoantibodies that bound to an intercellular substance (ICS) of skin and mucosa. Subsequently, skin biopsies revealed in vivo deposition of auto-antibodies in the epidermis of pemphigus ...
Gerald S. Lazarus, Gerald S. Lazarus, Kay H. Singer, Kay H. Singer   +3 more
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Molecular mechanisms of immunosuppression

Journal of Autoimmunity, 1992
The immunosuppressive drug cyclosporin A (CsA, Sandimmun, SIM) is currently being evaluated in a variety of autoimmune disorders with some remarkable successes. Despite the wide empiric application of CsA, the precise mechanism of action of this drug remains elusive.
Peter Hiestand, Gerhard Zenke, Max H. Schreier, Elsebeth Andersen, Götz Baumann, Valérie F. J. Quesniaux, Roland H. Wenger   +6 more
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Molecular mechanisms of photocarcinogenesis

Frontiers in Bioscience, 2002
Photocarcinogenesis represents the accumulation of genetic changes as well as immune system modulation, which ultimately lead to the development of skin cancers. The recent advances in molecular and cellular biology have clarified the mechanisms of photocarcinogenesis, including the formation of DNA photoproducts, DNA repair, mutation of proto ...
Yasuhiro Matsumura, Honnavara N. Ananthaswamy   +1 more
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Molecular Mechanisms of Oncogenesis [PDF]

, 1990
Cellular oncogenes (c-oncs) have been highly conserved throughout evolution and subserve important roles in growth and development. Both in development and the neoplastic state, c-oncs appear to collaborate rather than function independently. Cellular oncogenes are activated in the neoplastic process by four (nonviral) mechanisms; (a) chromosomal ...
Thomas A. Seemayer, Webster K. Cavenee
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Molecular Mechanisms of Lymphangiogenesis

International Journal of Hematology, 2004
Although the process of vascular development has been well documented, little is understood about lymphatic vasculature formation, despite its importance in normal and pathologic conditions. The dysfunction or abnormal growth of lymphatic vessels is associated with lymphedema and cancer metastasis. The recent discovery of lymphangiogenic growth factors
Meiko Takahashi, Hajime Kubo, Takanobu Yoshimoto   +2 more
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Molecular mechanisms of cholestasis

Wiener Medizinische Wochenschrift, 2006
Recent progress has enhanced our understanding of the pathogenesis of cholestatic liver diseases. Mutations in genes encoding for hepatobiliary transport systems can cause hereditary cholestatic syndromes and exposure to cholestatic agents (drugs, hormones, inflammatory cytokines) can lead to reduced expression and function of hepatic uptake and ...
Gernot Zollner, Michael Trauner
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Molecular mechanisms of sepsis [PDF]

Langenbeck's Archives of Surgery, 1998
Today a great number of problems in the field of bacterial sepsis remain to be solved. Understanding the molecular mechanisms of one of the most important bacterial products in the pathogenesis of sepsis - endotoxin may contribute to innovative and more effective therapies.
Alexander Woltmann, E. T. Rietschel, L. Hamann, J. Gerdes, H-P Bruch, A. J. Ulmer   +5 more
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