Results 1 to 10 of about 1,056,051 (329)

Towards Multitarget Testing in Molecular Microbiology [PDF]

International Journal of Microbiology, 2013
Advantages of PCR assays over more conventional culture-based diagnostics include significantly higher sensitivities and shorter turnaround times. They are particularly useful when patient treatment has already been initiated or for specimens that may ...
Deborah Steensels, Anne Vankeerberghen, Hans De Beenhouwer   +2 more
doaj   +5 more sources

Legionella: Molecular Microbiology [PDF]

Emerging Infectious Diseases, 2009
Thomas J. Marrie
doaj   +3 more sources

Foodborne Pathogens: Microbiology and Molecular Biology [PDF]

Emerging Infectious Diseases, 2006
Foodborne pathogens can create a considerable amount of work at state and local health departments. Between foodborne outbreaks, restaurant inspections, environmental testing, botulism reports, customer complaints, and confirmation of isolates referred for testing, many health department resources are directed toward these pathogens and preventing ...
Sharon Balter
doaj   +7 more sources

Plasmodium sporozoites require the protein B9 to invade hepatocytes

iScience, 2023
Summary: Plasmodium sporozoites are transmitted to a mammalian host during blood feeding by an infected mosquito and invade hepatocytes for initial replication of the parasite into thousands of erythrocyte-invasive merozoites.
Priyanka Fernandes, Manon Loubens, Carine Marinach, Romain Coppée, Ludivine Baron, Morgane Grand, Thanh-Phuc Andre, Soumia Hamada, Anne-Claire Langlois, Sylvie Briquet, Philippe Bun, Olivier Silvie   +11 more
doaj   +1 more source

Moraxella catarrhalis evades neutrophil oxidative stress responses providing a safer niche for nontypeable Haemophilus influenzae

iScience, 2022
Summary: Moraxella catarrhalis and nontypeable Haemophilus influenzae (NTHi) are pathogenic bacteria frequently associated with exacerbation of chronic obstructive pulmonary disease (COPD), whose hallmark is inflammatory oxidative stress.
Sonia Nicchi, Fabiola Giusti, Stefano Carello, Sabrina Utrio Lanfaloni, Simona Tavarini, Elisabetta Frigimelica, Ilaria Ferlenghi, Silvia Rossi Paccani, Marcello Merola, Isabel Delany, Vincenzo Scarlato, Domenico Maione, Cecilia Brettoni   +12 more
doaj   +1 more source

Transmission of pLVPK-like virulence plasmid in Klebsiella pneumoniae mediated by an Incl1 conjugative helper plasmid

iScience, 2022
Summary: We previously reported the recovery of five ST11 carbapenem resistant hypervirulent Klebsiella pneumoniae (CR-HvKP) strains that harbored pLVPK-like virulence plasmids, yet molecular mechanisms underlying acquisition of virulence plasmid by ST11
Xuemei Yang, Miaomiao Xie, Qi Xu, Lianwei Ye, Chen Yang, Ning Dong, Edward Wai-Chi Chan, Rong Zhang, Sheng Chen   +8 more
doaj   +1 more source

Functional and Safety Characterization of Weissella paramesenteroides Strains Isolated from Dairy Products through Whole-Genome Sequencing and Comparative Genomics

Dairy, 2022
Strains belonging to the Weissella genus are frequently recovered from spontaneously fermented foods. Their functional, microbial-modulating, and probiotic traits enhance not only the sensorial properties but also the nutritional value, beneficial ...
Ilias Apostolakos, Spiros Paramithiotis, Marios Mataragas   +2 more
doaj   +1 more source

Reactive oxygen species accelerate de novo acquisition of antibiotic resistance in E. coli

iScience, 2023
Summary: Reactive oxygen species (ROS) produced as a secondary effect of bactericidal antibiotics are hypothesized to play a role in killing bacteria. If correct, ROS may play a role in development of de novo resistance.
Wenxi Qi, Martijs J. Jonker, Wim de Leeuw, Stanley Brul, Benno H. ter Kuile   +4 more
doaj   +1 more source

Structural insights into the inhibition of bacterial RecA by naphthalene polysulfonated compounds

iScience, 2021
Summary: As a promising target for alternative antimicrobials, bacterial recombinase A (RecA) protein has attracted much attention for its roles in antibiotic-driven SOS response and mutagenesis. Naphthalene polysulfonated compounds (NPS) such as suramin
Ziyuan Zhou, Qing Pan, Xinchen Lv, Jing Yuan, Yang Zhang, Ming-Xia Zhang, Ming Ke, Xiao-Mei Mo, Yong-Li Xie, Yingxia Liu, Ting Chen, Mingchan Liang, Feng Yin, Lei Liu, Yiqing Zhou, Kun Qiao, Rui Liu, Zigang Li, Nai-Kei Wong   +18 more
doaj   +1 more source

Nonstructural protein 1 widespread RNA decay phenotype varies among coronaviruses

iScience, 2023
Summary: Extensive remodeling of host gene expression by nonstructural protein 1 (nsp1) of coronaviruses is a well-documented and conserved aspect of coronavirus-host takeover.
Yahaira Bermudez, Jacob Miles, Mandy Muller   +2 more
doaj   +1 more source