Results 141 to 150 of about 1,092,921 (340)

Microbiome analysis in Asia’s largest watershed reveals inconsistent biogeographic pattern and microbial assembly mechanisms in river and lake systems

iScience
Summary: Microorganisms are critical to the stability of aquatic environments, and understanding the ecological mechanisms of microbial community is essential.
Xi Liu, Lu Zhang, Yingcai Wang, Sheng Hu, Jing Zhang, Xiaolong Huang, Ruiwen Li, Yuxin Hu, Huaiying Yao, Zhi Wang   +9 more
doaj   +1 more source

Tetrahedral DNA Nanostructure‐Based Biomimetic Nanovesicles Attenuate Sepsis‐Associated ARDS by Suppressing Glycolysis via the BMAL1/PFKFB3 Axis

Advanced Science, EarlyView.
Upon inhalation, RM@TNT could persist long‐term in the diseased lungs, while undergoing disintegration to release TNT specifically within the ROS‐rich pathological microenvironments of SA‐ARDS. The released TNT was then precisely delivered to AMs via Tuftsin, where it released Nob intracellularly to activate BMAL1 expression, thus inhibiting AM ...
Yunlong Zhang, Bin Li, Zhijin Fan, Yan Yan, Fei Ma, Changting He, Shiping Liu, Mingliang Pan, Zhou Pan, Huijuan Wang, Xinting Fu, Jiamei Wang, Yue Jia, Qin Gu, Duo Jiang, Xueting Liu, Bohua Ren, Qinqin Wang, Yuehua Hei, Han Duan, Yanqiu Wu, Zihui Wei, Liying Zhan, Yuhui Liao   +23 more
wiley   +1 more source

Transcriptomic and proteomic analysis reveals the mechanism of chicken cecum response to Salmonella enterica serovar Enteritidis inoculation

iScience
Summary: Salmonella enterica serovar Enteritidis (SE) incurs foodborne illnesses and poses a severe threat to poultry industry and human health. However, the molecular mechanisms underlying chicken responding to SE inoculation remain elusive.
Yuanmei Wang, Liying Liu, Yanan Zhao, Yanru Ren, Xiuxiu Miao, Yaning Dong, Lewen Liu, Xianyao Li   +7 more
doaj   +1 more source

Molecular microbiology

, 2021
Tran, Nam, Whitman, Jeffrey
openaire   +1 more source

Crystal Facet‐Polysaccharide Matching in CFS‐P Nanocrystals Drives Fungal Uptake, Vacuole Destruction, and Selective Antifungal Activity

Advanced Science, EarlyView.
Facet‐engineered PVP‐capped CuFeSe2 nanocrystals exhibit potent, selective antifungal activity by strongly binding cell‐wall mannan, enabling vacuolar entry and organelle disruption. High‐index facets show superior mannan affinity, validated by theoretical calculations and experiments. CFS‐P induces vacuolar cavitation, mitochondrial abnormalities, and
Zhaohui Wang, Xiaojin Deng, Xujuan Huang, Yuhang Pan, Yao Qin, Lu Zhang, Le Xu, Tianyi Qin, Deteng Zhang, Yi Ma, Yalong Wang   +10 more
wiley   +1 more source

Infection and resistance mechanisms of phage vB_VpM-PP270 in Vibrio parahaemolyticus via capsular polysaccharide

iScience
Summary: Vibrio parahaemolyticus is a major foodborne pathogen that threatens public health and aquaculture, necessitating alternative biocontrol strategies such as phage therapy.
Zhu Xihui, Hong Junshan, Xu Jiayin, Tang Luqi, Li Pei, Jiang Wei, Zhang Wei   +6 more
doaj   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Mechanisms of Pericyte‐Mediated Cancer Metastasis

Advanced Science, EarlyView.
Pericytes play multifarious roles in promoting cancer metastasis by facilitating metastatic cancer cell dissemination, circulating tumor cell survival, tissue extravasation, premetastatic niche formation, and metastatic tumor growth. These cells have intertwined interactions with vascular endothelial cells to modulate cancer cell behavior and ...
Ziheng Guo, Yihai Cao
wiley   +1 more source

The sequence of events of enteropathogenic E. coli’s type III secretion system translocon assembly

iScience
Summary: Many bacterial pathogens employ the type III secretion system (T3SS), a specialized complex that transports effector proteins that manipulate various cellular processes.
Jenia Gershberg, May Morhaim, Irina Rostrovsky, Jerry Eichler, Neta Sal-Man   +4 more
doaj   +1 more source

Molecular Methods in Food Safety Microbiology: Interpretation and Implications of Nucleic Acid Detection [PDF]

, 2014
Siele Ceuppens, Dan Li, Mieke Uyttendaele, Pierre Renault, R. Paul Ross, Marc Van Ranst, Luca Cocolin, John Donaghy   +7 more
openalex   +1 more source