Results 31 to 40 of about 1,088,260 (325)

Microbial degradation of dimethylsulphide and related C1-sulphur compounds: organisms and pathways controlling fluxes of sulphur in the biosphere [PDF]

open access: yes, 2010
Dimethylsulphide (DMS) plays a major role in the global sulphur cycle. It has important implications for atmospheric chemistry, climate regulation, and sulphur transport from the marine to the atmospheric and terrestrial environments.
Boden, Rich   +2 more
core   +1 more source

Structural modeling and functional analysis of the essential ribosomal processing protease Prp from Staphylococcus aureus [PDF]

open access: yes, 2017
In Firmicutes and related bacteria, ribosomal large subunit protein L27 is encoded with a conserved N-terminal extension that is removed to expose residues critical for ribosome function. Bacteria encoding L27 with this N-terminal extension also encode a
Christie, Gail E.   +3 more
core   +2 more sources

A distinct sortase SrtB anchors and processes a streptococcal adhesin AbpA with a novel structural property. [PDF]

open access: yes, 2016
Surface display of proteins by sortases in Gram-positive bacteria is crucial for bacterial fitness and virulence. We found a unique gene locus encoding an amylase-binding adhesin AbpA and a sortase B in oral streptococci.
Haase, EM   +6 more
core   +1 more source

Genotypic and phenotypic characteristics of Cronobacter species, with particular attention to the newly reclassified species C. helveticus, C. pulveris, and C. zurichensis [forthcoming] [PDF]

open access: yes, 2014
In 2013, Enterobacter helveticus, E. pulveris and E. turicensis, were reclassified as Cronobacter helveticus, C. pulveris and C. zurichensis, respectively. Previously these species had been used as negative controls for some Cronobacter detection assays.
Forsythe, SJ   +3 more
core   +1 more source

Glutamate signaling mediates C. elegans behavioral plasticity to pathogens

open access: yesiScience, 2022
Summary: In Caenorhabditis elegans, sensory neurons mediate behavioral response to pathogens. However, how C. elegans intergrades these sensory signals via downstream neuronal and molecular networks remains largely unknown. Here, we report that glutamate
Chun-Ying Yu, Howard C. Chang
doaj   +1 more source

Target Identification of an Antimalarial Oxaborole Identifies AN13762 as an Alternative Chemotype for Targeting CPSF3 in Apicomplexan Parasites

open access: yesiScience, 2020
Summary: Boron-containing compounds represent a promising class of molecules with proven efficacy against a wide range of pathogens, including apicomplexan parasites.
Valeria Bellini   +7 more
doaj   +1 more source

Molecular Microbiology [PDF]

open access: yes, 2015
Background Nucleic acid (NA) amplification techniques are now commonly used to diagnose and manage patients with infectious diseases. The growth in the number of Food and Drug Administration–approved test kits and analyte-specific reagents has facilitated the use of this technology in clinical laboratories.
openaire   +1 more source

The trans-activation domain of the sporulation response regulator Spo0A revealed by X-ray crystallography [PDF]

open access: yes, 2000
Sporulation in Bacillus involves the induction of scores of genes in a temporally and spatially co-ordinated programme of cell development. Its initiation is under the control of an expanded two-component signal transduction system termed a phosphorelay.
Baldus J.M.   +32 more
core   +1 more source

Substitutions in the redox-sensing PAS domain of the NifL regulatory protein define an inter-subunit pathway for redox signal transmission [PDF]

open access: yes, 2011
The Per-ARNT-Sim (PAS) domain is a conserved a/ß fold present within a plethora of signalling proteins from all kingdoms of life. PAS domains are often dimeric and act as versatile sensory and interaction modules to propagate environmental signals to ...
Ayers   +34 more
core   +1 more source

Functional compartmentalization of Rad9 and Hus1 reveals diverse assembly of the 9-1-1 complex components during the DNA damage response in Leishmania [PDF]

open access: yes, 2016
The Rad9-Rad1-Hus1 (9-1-1) complex is a key component in the coordination of DNA damage sensing, cell cycle progression and DNA repair pathways in eukaryotic cells. This PCNA-related trimer is loaded onto RPA-coated single stranded DNA and interacts with
Damasceno, Jeziel D.   +5 more
core   +1 more source

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