Results 61 to 70 of about 1,085,190 (301)

Complex regulation of the aflatoxin biosynthesis gene cluster of Aspergillus flavus in relation to various combinations of water activity and temperature [PDF]

, 2009
A microarray analysis was performed to study the effect of varying combinations of water activity and temperature on the activation of aflatoxin biosynthesis genes in Aspergillus flavus grown on YES medium. Generally A.
Abdel-Hadi, Ahmed, Geisen, Rolf, Magan, Naresh, Schmidt-Heydt, Markus   +3 more
core   +1 more source

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

Virulence Regulation in Borrelia burgdorferi

Microorganisms
Borrelia burgdorferi, the causative agent of Lyme disease, is the most common vector-borne disease in the United States. Compared with other bacterial pathogens, B. burgdorferi has many unique features.
Sierra George, Zhiming Ouyang
doaj   +1 more source

Proteolysis of Rab32 by Salmonella GtgE induces an inactive GTPase conformation

iScience, 2021
Summary: Rab GTPases are central regulators of intracellular vesicular trafficking. They are frequently targeted by bacterial pathogens through post-translational modifications. Salmonella typhimurium secretes the cysteine protease GtgE during infection,
Sergey Savitskiy, Rudolf Wachtel, Danial Pourjafar-Dehkordi, Hyun-Seo Kang, Vanessa Trauschke, Don C. Lamb, Michael Sattler, Martin Zacharias, Aymelt Itzen   +8 more
doaj   +1 more source

Marine crude-oil biodegradation: a central role for interspecies interactions [PDF]

, 2012
The marine environment is highly susceptible to pollution by petroleum, and so it is important to understand how microorganisms degrade hydrocarbons, and thereby mitigate ecosystem damage. Our understanding about the ecology, physiology, biochemistry and
Folwell, Benjamin D, McGenity, Terry J, McKew, Boyd A, Sanni, Gbemisola O   +3 more
core   +1 more source

Mechanically Stable and Tunable Photoactivated Peptide‐Based Hydrogels for Soft Tissue Adhesion

Advanced Functional Materials, EarlyView.
A collagen‐like peptide hydrogel platform is developed using supramolecular self‐assembly and light‐triggered crosslinking. It creates mechanically stable, tunable hydrogels with cytocompatibility and biodegradability, making them potential soft tissue adhesives.
Alex Ross, Daniel Nguyen, Aidan J. MacAdam, German A. Mercado Salazar, Micaela Gianetti, Ramis Ileri, Marc Ruel, Erik J. Suuronen, Emilio I. Alarcon   +8 more
wiley   +1 more source

Microbiome and Dental Changes in Horses Fed a High Soluble Carbohydrate Diet

Animals
This study investigated the oral microbiome of horses maintained on a high soluble carbohydrate diet based on sugarcane, in comparison to those fed a pasture-based diet composed of Cynodon spp., aiming to identify associations between dietary intake, the
Milena Domingues Lacerenza, Júlia de Assis Arantes, Gustavo Morandini Reginato, Gabriela Luiza Fagundes Finardi, Pedro Henrique Marchi, Thiago Henrique Annibale Vendramini, Rodrigo Romero Corrêa, Pamela Aparecida Maldaner Pereira, Carlos Augusto Araújo Valadão, Renata Gebara Sampaio Dória   +9 more
doaj   +1 more source

A gradient-forming MipZ protein mediating the control of cell division in the magnetotactic bacterium Magnetospirillum gryphiswaldense [PDF]

, 2019
Cell division needs to be tightly regulated and closely coordinated with other cellular processes to ensure the generation of fully viable offspring.
Bramkamp, M., Corrales-Guerrero, L., Mueller, F., Osorio-Valeriano, M., Plitzko, J., Schueler, D., Thanbichler, M., Toro-Nahuelpan, M., Zwiener, T.   +8 more
core   +1 more source

In Situ 3D Bioprinting: Impact of Cross‐Linking on the Adhesive Properties of Hydrogels

Advanced Functional Materials, EarlyView.
In situ 3D bioprinting enables the direct deposition of cell‐laden, adhesive biomaterials for on‐site tissue regeneration. This review provides a comprehensive overview of how cross‐linking influences the bioadhesive properties of hydrogels used in 3D bioprinting, highlighting cross‐linking triggers, bioadhesion mechanisms, polymer interpenetration ...
Odile Romero Fernandez, Mulazim Hussain Asim, Shumaila Arshad, Gergely Kali, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

Origin of replication discovery for environmentally isolated Pantoea strain enables expression of heterologous proteins, pathways and products

iScience
Summary: Leveraging predicted origin sequences from a previously characterized groundwater plasmidome, we constructed a barcoded plasmid library to screen for previously unknown origins.
Alex Codik, Ankita Kothari, Hualan Liu, Benjamin L. Weinberg, Trenton K. Owens, Aparajitha Srinivasan, Alex Rivier, Thomas Eng, Adam P. Arkin, Adam M. Deutschbauer, Aindrila Mukhopadhyay   +10 more
doaj   +1 more source