Results 51 to 60 of about 3,774,726 (329)
Survival benefits in mimicry: a quantitative framework [PDF]
Journal of Theoretical Biology, Vol. 259, pages 462-468 (2009), 2008 Mimicry is a resemblance between species that benefits at least one of the species. It is a ubiquitous evolutionary phenomenon particularly common among prey species, in which case the advantage involves better protection from predation. We formulate a mathematical description of mimicry among prey species, to investigate benefits and disadvantages of ...
arxiv +1 more source
Sarcoidosis, Cancer and Molecular Mimicry [PDF]
International Journal of Immunopathology and Pharmacology, 2013 Molecular mimicry seems to be the most important factor for the heterogeneous clinical presentation and the immunopathogenesis of sarcoidosis. Molecular mimicry may occur as a result of altered activity of oncogenes. This can lead to crossed-type mediated body reactions targeting structurally similar sections or regions from the tissue homeostasis ...
Uwe Wollina, Georgi Tchernev
openaire +2 more sources
From Anti-SARS-CoV-2 Immune Responses to COVID-19 via Molecular Mimicry
Antibodies, 2020 Aim: To define the autoimmune potential of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection. Methods: Experimentally validated epitopes cataloged at the Immune Epitope DataBase (IEDB) and present in SARS-CoV-2 were analyzed for ...
D. Kanduc
semanticscholar +1 more source
Decoding the relationship between cow’s milk proteins and development of type 1 diabetes mellitus [PDF]
Archives of Endocrinology and MetabolismObjective To analyze in silico the evidence of molecular mimicry between human beta-cell autoantigens and cow’s milk proteins as a potential type 1 diabetes mellitus (T1DM) trigger.
Luís Jesuino de Oliveira Andrade +5 more
doaj +1 more source
Pathogens, 2022 Clinical epidemiological studies have reported that viral infections cause autoimmune pathology in humans. Host-pathogen protein sequences and structure-based molecular mimicry cause autoreactive T cells to cross-activate.
Sara Begum +8 more
doaj +1 more source
Heat shock proteins may be a missing link between febrile infection and cancer tumor rejection via autoantigen molecular mimicry [PDF]
arXiv, 2023 Numerous epidemiological studies suggest febrile infections could confer long-term immunity to certain types of cancers, though the precise mechanisms for this phenomenon remain unclear. Systemic heat-shock responses to fever may be key to understanding the overlapping outcomes of immune responses to infection and cancer. To investigate this hypothesis,
arxiv
Lack of Evidence for Molecular Mimicry in HIV-Infected Subjects. [PDF]
PLoS ONE, 2015 Previous studies in HIV patients have reported autoantibodies to several human proteins, including erythropoietin (EPO), interferon-α (IFN-α), interleukin-2 (IL-2), and HLA-DR, as potential mediators of anemia or immunosuppression.
Peter D Burbelo +4 more
doaj +1 more source
Stochastic effects in autoimmune dynamics [PDF]
Frontiers in Physiology 9, 45 (2018), 2018 Among various possible causes of autoimmune disease, an important role is played by infections that can result in a breakdown of immune tolerance, primarily through the mechanism of "molecular mimicry". In this paper we propose and analyse a stochastic model of immune response to a viral infection and subsequent autoimmunity, with account for the ...
arxiv +1 more source
Cell Death Discovery, 2020 The hand of molecular mimicry in shaping SARS-CoV-2 evolution and immune evasion remains to be deciphered. Here, we report 33 distinct 8-mer/9-mer peptides that are identical between SARS-CoV-2 and the human reference proteome.
A. Venkatakrishnan +5 more
semanticscholar +1 more source
A possible role for autoimmunity through molecular mimicry in alphavirus mediated arthritis
Scientific Reports, 2020 Alphaviral infections are foremost in causing debilitating clinical outcomes in humans characterized by rheumatic arthritis like conditions. Though the presence of virus in joints and associated inflammation has been implicated as one of the reasons for ...
Siva Sai Krishna Venigalla +2 more
semanticscholar +1 more source