Results 81 to 90 of about 3,245,847 (271)

Lignin Mimicking Protein Methylation Augments the Efficacy of FOLFOX Chemotherapy by Anchoring Thymidylate Synthase

open access: yesAdvanced Materials, EarlyView.
Lignin‐mimicking protein methylation can enhance the efficacy and mitigate the toxicity of the classic FOLFOX chemotherapy regimen. ABSTRACT FOLFOX has served as the standard chemotherapy regimen for advanced stages, specifically in the treatment of pancreatic, colorectal, and bladder cancers.
Shiyao Song   +14 more
wiley   +1 more source

Molecular mimicry in autoimmune disease [PDF]

open access: yesArchives of Disease in Childhood, 1998
The origins of autoimmune disease are multifactorial. Environmental factors and a genetic predisposition result in tissue injury caused by autoreactive T cells or antibodies. Usually a single organ or individual cell type is affected in the absence of gross abnormalities of the immune system.
openaire   +2 more sources

Hydrogel‐Based Airway‐on‐Tube With Perfusable Endothelial Lumen and Outward Epithelialization

open access: yesAdvanced Materials, EarlyView.
A hydrogel‐based airway‐on‐tube platform featuring a perfusable endothelial lumen and outward epithelialization is presented. The system supports primary human bronchial epithelial and lung microvascular endothelial coculture under air‐liquid interface conditions.
Ali Doryab   +8 more
wiley   +1 more source

Molecular Mimicry in Mercury Toxicology

open access: yes, 2016
Molecular mimicry occurs when one molecular entity is “mistaken” for another by cellular or other biological processes, and is thought to arise from structural similarities between the two molecules in question.
Andrew R. S. Ross (767634)   +6 more
core   +1 more source

Emerging strategies for targeting vasculogenic mimicry in breast cancer treatment

open access: yesDiscover Oncology
Breast cancer represents the most commonly diagnosed malignancy worldwide and is the fourth leading cause of cancer-related mortality. Approximately 2.3 million new cases of breast cancer were diagnosed worldwide in 2022, accounting for 11.6% of all ...
Nare Sekoba   +3 more
doaj   +1 more source

Morbid Sequences Suggest Molecular Mimicry between Microbial Peptides and Self-Antigens: A Possibility of Inciting Autoimmunity

open access: yesFrontiers in Microbiology, 2017
Understanding etiology of autoimmune diseases has been a great challenge for designing drugs and vaccines. The pathophysiology of many autoimmune diseases may be attributed to molecular mimicry provoked by microbes.
Susanta Pahari   +6 more
doaj   +1 more source

Clustomesogen Showing Sub‐Zero Liquid Crystal Properties: Supramolecular Assembly Between Cs2[Mo6Ii8(OCOC2F5)6] and Hexaethylenoxide Containing Mesogenic Dimers

open access: yesAdvanced Materials, EarlyView.
Associating a red‐NIR phosphorescent octahedral hexanuclear molybdenum cluster compound with hexaethyleneoxide chains bearing mesogenic units on both ends leads to an emissive hybrid liquid crystal showing mesomorphism on a very unusual temperature range down to −25°C.
Killiann Heinz   +11 more
wiley   +1 more source

Bioinspired Adaptive Surfaces for Intelligent Liquid Manipulation: Progressing From Passive and Active to Hybrid Strategies

open access: yesAdvanced Materials, EarlyView.
This review examines passive, active, and hybrid liquid manipulation strategies, highlighting hybrid approaches as an emerging route to reconcile energy efficiency with adaptive control. By actively reconstructing passive surfaces to store programmable interfacial energy, hybrid systems enable flexible yet low‐power liquid transport, with perspectives ...
Jiaqi Miao   +3 more
wiley   +1 more source

T Cell Allorecognition via Molecular Mimicry [PDF]

open access: yes, 2009
SummaryT cells often alloreact with foreign human leukocyte antigens (HLA). Here we showed the LC13 T cell receptor (TCR), selected for recognition on self-HLA-B∗0801 bound to a viral peptide, alloreacts with B44 allotypes (HLA-B∗4402 and HLA-B∗4405 ...
Clements, Craig S.   +19 more
core   +1 more source

Anti-ganglioside anti-idiotypic vaccination: more than molecular mimicry.

open access: yesFrontiers in Oncology, 2012
Surgery, chemotherapy, and radiation therapy are standard modalities for cancer treatment, but the effectiveness of these treatments has reached a plateau. Thus, other strategies are being explored to combine with the current treatment paradigms in order
Ana María eHernández   +2 more
doaj   +1 more source

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