Results 1 to 10 of about 4,131 (170)
Vasculogenic mimicry in carcinogenesis and clinical applications [PDF]
Journal of Hematology & Oncology, 2020 Distinct from classical tumor angiogenesis, vasculogenic mimicry (VM) provides a blood supply for tumor cells independent of endothelial cells. VM has two distinct types, namely tubular type and patterned matrix type.
Qingxi Luo +9 more
doaj +3 more sources
Human placental exposure to pollutant nanoparticles: uptake, translocation and functional impact
The Journal of Physiology, EarlyView.Abstract figure legend Prenatal exposure to pollutant nanoparticles has been increasingly investigated due to concerns about their potential effects on placental function and pregnancy outcomes. Maternal inhalation of pollutant nanoparticles can result in a pro‐inflammatory response; particles can also translocate across the alveolus epithelial barrier
Katherine L. Bethell +3 more
wiley +1 more source
RNA Modifications in Tumor Microenvironment: A New Dimension for Cancer Treatment
MedComm, Volume 7, Issue 7, July 2026.Tumor initiation and progression depend on a supportive and highly heterogeneous tumor microenvironment (TME). RNA modifications regulate signaling pathways and cytokine networks that shape TME dynamics, facilitating interactions between cancer cells and noncancerous stromal cells, and ultimately promoting immune evasion and tumor progression ...
Qiwen Li +3 more
wiley +1 more source
VE-Cadherin modulates β-catenin/TCF-4 to enhance Vasculogenic Mimicry
Cell Death and Disease, 2023 Vasculogenic Mimicry (VM) refers to the capacity to form a blood network from aggressive cancer cells in an independent way of endothelial cells, to provide nutrients and oxygen leading to enhanced microenvironment complexity and treatment failure.
Daniel Delgado-Bellido +11 more
doaj +1 more source
Intratumoral Microbiota in Tumor: Current Understandings and Future Perspectives
MedComm, Volume 7, Issue 7, July 2026.Intratumoral bacteria are emerging as active regulators of cancer evolution rather than bystanders. This review outlines how tumor‐resident microbes drive tumor initiation and growth by inducing genomic instability, epigenetic reprogramming, oncogenic signaling, and chronic inflammation, while promoting metastatic spread via invasion, angiogenesis ...
Jiawei Chen +6 more
wiley +1 more source
Journal of Experimental & Clinical Cancer Research, 2010 Background Epithelial ovarian cancer is one of the most malignant cancers in women because metastasis occurs in the most of patients by the time of diagnosis. Cancer cells have strong capacity to form angiogenesis or vasculogenic mimicry, which plays the
Zhu Pengfei +4 more
doaj +1 more source
An update on the landscape of collagen bioactive fragments
The FEBS Journal, Volume 293, Issue 13, Page 4064-4084, July 2026.The remodeling of the extracellular matrix releases collagen bioactive fragments, which exert molecular functions and regulate numerous biological processes via several signaling pathways. Here, we summarize the latest findings describing the roles of major bioactive fragments from collagens I, IV, VI, and XVIII in various physiological and ...
Sylvie Ricard‐Blum, Julie Fradette
wiley +1 more source
Cell Death and Disease, 2021 In nasopharyngeal carcinoma (NPC), the treatment of tumor metastasis and recurrence is challenging and is associated with poor clinical efficacy. Vasculogenic mimicry (VM) is a new blood-supply model of malignant tumor that is closely related to tumors ...
Yunfan Luo +8 more
doaj +1 more source
Vasculogenic mimicry persists during glioblastoma xenograft growth
Glioma, 2018 Background: Vasculogenic mimicry (VM) describes the functional plasticity of aggressive tumor cells to form newly recognized microcirculation, lined by tumor cells rather than endothelial cells, in solid tumors.
Cong Li +7 more
doaj +1 more source
Pathology and Oncology Research, 2023 CVM-1118 (foslinanib) is a phosphoric ester compound selected from 2-phenyl-4-quinolone derivatives. The NCI 60 cancer panel screening showed CVM-1125, the major active metabolite of CVM-1118, to exhibit growth inhibitory and cytotoxic effects at ...
Lifen Shen +9 more
doaj +1 more source