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Vasculogenic mimicry

Journal of Oral and Maxillofacial Pathology, 2023
Vasculogenic mimicry (VM) refers to the ability of malignant cells to form microvascular channels, having nature of blood vessels but are not endothelium lined. These channels contain blood cells & plasma and provide sufficient nutrient supply to the cancerous cells to meet their metabolic demands. VM can be seen in various tumors and is associated
Pandiar, Deepak, Smitha, T, Krishnan, Reshma Poothakulath   +2 more
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Vasculogenic Mimicry and Tumor Angiogenesis [PDF]

The American Journal of Pathology, 2000
Tumors require a blood supply for growth and hematogenous dissemination. Much attention has been focused on the role of angiogenesis-the recruitment of new vessels into a tumor from pre-existing vessels. However, angiogenesis may not be the only mechanism by which tumors acquire a microcirculation.
R, Folberg, M J, Hendrix, A J, Maniotis
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HOX Transcript Antisense RNA HOTAIR Abrogates Vasculogenic Mimicry by Targeting the AngiomiR-204/FAK Axis in Triple Negative Breast Cancer Cells

Non-Coding RNA, 2020
HOX transcript antisense RNA (HOTAIR) is an oncogenic long non-coding RNA frequently overexpressed in cancer. HOTAIR can enhance the malignant behavior of tumors by sponging microRNAs with tumor suppressor functions.
Allan Lozano-Romero, Horacio Astudillo-de la Vega, María Cruz del Rocío Terrones-Gurrola, Laurence A. Marchat, Daniel Hernández-Sotelo, Yarely M. Salinas-Vera, Rosalío Ramos-Payan, Macrina B. Silva-Cázares, Stephanie I. Nuñez-Olvera, Olga N. Hernández-de la Cruz, César López-Camarillo   +10 more
doaj   +1 more source

Vascular co‐option and vasculogenic mimicry mediate resistance to antiangiogenic strategies

Cancer Reports, 2022
Background The concept that all the tumors need the formation of new vessels to grow inspired the hypothesis that inhibition of angiogenesis would have led to “cure” cancer.
Francesco Pezzella, Domenico Ribatti
doaj   +1 more source

Marine Bromophenol Bis(2,3,6-Tribromo-4,5-Dihydroxybenzyl)ether Inhibits Angiogenesis in Human Umbilical Vein Endothelial Cells and Reduces Vasculogenic Mimicry in Human Lung Cancer A549 Cells

Marine Drugs, 2021
Angiogenesis, including the growth of new capillary blood vessels from existing ones and the malignant tumors cells formed vasculogenic mimicry, is quite important for the tumor metastasis.
Songtao Dong, Zhongyuan Chen, Li Wang, Yankai Liu, Dimitrios Stagos, Xiukun Lin, Ming Liu   +6 more
doaj   +1 more source

Application of IVIM-DWI in Detecting the Tumor Vasculogenic Mimicry Under Antiangiogenesis Combined With Oxaliplatin Treatment

Frontiers in Oncology, 2020
Objectives: This study aimed to detect the time window of vascular normalization during anti-vascular treatment using intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI). Simultaneously, we evaluated the tumor invasiveness and vasculogenic
Jianye Liang, Jianye Liang, Zhipeng Li, Jing Li, Chuan Peng, Wei Dai, Haoqiang He, Sihui Zeng, Chuanmiao Xie   +8 more
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An Overview of Vasculogenic Mimicry in Breast Cancer [PDF]

Frontiers in Oncology, 2020
Vasculogenic mimicry (VM) is the formation of vascular channels lacking endothelial cells. These channels are lined by tumor cells with cancer stem cell features, positive for periodic acid-Schiff, and negative for CD31 staining. The term VM was introduced by Maniotis et al.
Marco A. Andonegui-Elguera, Yair Alfaro-Mora, Rodrigo Cáceres-Gutiérrez, Claudia Haydee Sarai Caro-Sánchez, Luis A. Herrera, Luis A. Herrera, José Díaz-Chávez   +6 more
openaire   +3 more sources

ZRANB2/SNHG20/FOXK1 Axis regulates Vasculogenic mimicry formation in glioma

Journal of Experimental & Clinical Cancer Research, 2019
Background Glioma is the most common intracranial neoplasm with vasculogenic mimicry formation as one form of blood supply. Many RNA-binding proteins and long non-coding RNAs are involved in tumorigenesis of glioma.
Xiaozhi Li, Yixue Xue, Xiaobai Liu, Jian Zheng, Shuyuan Shen, Chunqing Yang, Jiajia Chen, Zhen Li, Libo Liu, Jun Ma, Teng Ma, Yunhui Liu   +11 more
doaj   +1 more source

TEM8 marks neovasculogenic tumor-initiating cells in triple-negative breast cancer

Nature Communications, 2021
Vasculogenic mimicry (VM) contributes to the development of triple-negative breast cancer. In this study, the authors show that TEM8 is expressed in VM-forming breast cancer stem cells and it promotes stemness and VM differentiation capacity through a ...
Jiahui Xu, Xiaoli Yang, Qiaodan Deng, Cong Yang, Dong Wang, Guojuan Jiang, Xiaohong Yao, Xueyan He, Jiajun Ding, Jiankun Qiang, Juchuanli Tu, Rui zhang, Qun-Ying Lei, Zhi-min Shao, Xiuwu Bian, Ronggui Hu, Lixing Zhang, Suling Liu   +17 more
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Establishment and Characterization of Canine Mammary Gland Carcinoma Cell Lines With Vasculogenic Mimicry Ability in vitro and in vivo

Frontiers in Veterinary Science, 2020
Mammary tumors affect intact and elderly female dogs, and almost 50% of these cases are malignant. Cell culture offers a promising preclinical model to study this disease and creates the opportunity to deposit cell lines at a cell bank to allow greater ...
Patrícia de Faria Lainetti, Andressa Brandi, Antonio Fernando Leis Filho, Maria Carolina Mangini Prado, Priscila Emiko Kobayashi, Renée Laufer-Amorim, Carlos Eduardo Fonseca-Alves, Carlos Eduardo Fonseca-Alves   +7 more
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