Results 91 to 100 of about 1,727,695 (209)

1st INCF Workshop on Genetic Animal Models for Brain Diseases [PDF]

, 2011
The INCF Secretariat organized a workshop to focus on the “role of neuroinformatics in the processes of building, evaluating, and using genetic animal models for brain diseases” in Stockholm, December 13–14, 2009.
Holm Graessner, Olaf Riess
core   +2 more sources

Improving the power of gene set enrichment analyses

BMC Bioinformatics, 2019
Background Set enrichment methods are commonly used to analyze high-dimensional molecular data and gain biological insight into molecular or clinical phenotypes.
Joanna Roder, Benjamin Linstid, Carlos Oliveira   +2 more
doaj   +1 more source

Pvr expression regulators in equilibrium signal control and maintenance of Drosophila blood progenitors. [PDF]

, 2014
Blood progenitors within the lymph gland, a larval organ that supports hematopoiesis in Drosophila melanogaster, are maintained by integrating signals emanating from niche-like cells and those from differentiating blood cells.
Banerjee, Utpal, Evans, Cory J, Mondal, Bama Charan, Shim, Jiwon   +3 more
core   +1 more source

Resistance phenotype and clinical molecular epidemiology of carbapenem-resistant Klebsiella pneumoniae among pediatric patients in Shanghai

Infection and Drug Resistance, 2018
Dongxing Tian, Fen Pan, Chun Wang, Yan Sun, Hong Zhang Department of Clinical Laboratory, Shanghai Children’s Hospital, Shanghai Jiaotong University, Shanghai, China Background: Carbapenem-resistant Klebsiella pneumoniae (CRKP) has caused wide ...
Tian D, Pan F, Wang C, Sun Y, Zhang H
doaj  

Phenotype and Molecular Detection of Clarithromycin and Levofloxacin Resistance in Helicobacter pylori Clinical Isolates in Beijing

Infection and Drug Resistance, 2020
Chong-Hou Lok, Dong Zhu, Jia Wang, Yu-Tang Ren, Xuan Jiang, Shu-Jun Li, Xiu-Ying Zhao Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, People’s Republic of ChinaCorrespondence : Xiu-Ying ZhaoBeijing ...
Lok CH, Zhu D, Wang J, Ren YT, Jiang X, Li SJ, Zhao XY   +6 more
doaj  

Cloning of the Neurodegeneration Gene \u3cem\u3eDrop-Dead\u3c/em\u3e and Characterization of Additional Phenotypes of its Mutation [PDF]

, 2008
Mutations in the Drosophila gene drop-dead (drd) result in early adult lethality and neurodegeneration, but the molecular identity of the drd gene and its mechanism of action are not known.
Blumenthal, Edward M.
core   +1 more source

Neutrality: A Necessity for Self-Adaptation

, 2002
Self-adaptation is used in all main paradigms of evolutionary computation to increase efficiency. We claim that the basis of self-adaptation is the use of neutrality.
Igel, Christian, Toussaint, Marc
core   +5 more sources

The impact of histopathology and NAB2-STAT6 fusion subtype in classification and grading of meningeal solitary fibrous tumor/hemangiopericytoma. [PDF]

, 2019
Meningeal solitary fibrous tumor (SFT)/hemangiopericytoma (HPC) is a rare tumor with propensity for recurrence and metastasis. Although multiple classification schemes have been proposed, optimal risk stratification remains unclear, and the prognostic ...
Alexander, Brian M, Brastianos, Priscilla K, Brat, Daniel, Brown, Paul D, Caron, Alissa, Ferrarese, Fabio, Fritchie, Karen, Giannini, Caterina, Guajardo, Andrew, Haller, Florian, Jenkins, Sarah, Jensch, Kassandra, Kaplan, Alexander, Link, Michael, Louis, David N, Moskalev, Evgeny A, Perry, Arie, Raleigh, David R, Rodriguez, Fausto J, Rossi, Sabrina, Santagata, Sandro, Velázquez Vega, José E, Wu, Ashley   +22 more
core  

Computational genes: a tool for molecular diagnosis and therapy of aberrant mutational phenotype

BMC Bioinformatics, 2007
Background A finite state machine manipulating information-carrying DNA strands can be used to perform autonomous molecular-scale computations at the cellular level.
Ignatova Zoya, Zhang Gong, Martínez-Pérez Israel M, Zimmermann Karl-Heinz   +3 more
doaj   +1 more source

Understanding the impact of spatial immunophenotypes on the survival of endometrial cancer patients through the ProMisE classification

Cancer Immunology, Immunotherapy
Objectives We focused on how the immunophenotypes based on the distribution of CD8-positive tumor-infiltrating lymphocytes (TILs) relate to the endometrial cancer (EC) molecular subtypes and patients’ prognosis.
Satomi Hattori, Nobuhisa Yoshikawa, Wenting Liu, Tetsuya Matsukawa, Mei Kubokawa, Kosuke Yoshida, Masato Yoshihara, Satoshi Tamauchi, Yoshiki Ikeda, Akira Yokoi, Yusuke Shimizu, Kaoru Niimi, Hiroaki Kajiyama   +12 more
doaj   +1 more source