Results 31 to 40 of about 1,727,695 (209)
Targeted mutagenesis using CRISPR-Cas9 in the chelicerate herbivore Tetranychus urticae [PDF]
, 2020 The use of CRISPR-Cas9 has revolutionized functional genetic work in many organisms, including more and more insect species. However, successful gene editing or genetic transformation has not yet been reported for chelicerates, the second largest group ...
Dermauw, Wannes +5 more
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Scientific Reports, 2020 Autism spectrum disorder (ASD) is a continuum of neurodevelopmental disorders and needs new therapeutic approaches. Recently, oxytocin (OXT) showed potential as the first anti-ASD drug.
Machi Horiai +13 more
doaj +1 more source
Molecular Phenotypes of Atherosclerosis [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2004 The initiation and progression of atherosclerosis appears driven by a combination of genetic and environmental factors. Access to circulating lipoproteins or to molecules shed into the blood from arterial wall cells permits genetic diversity to be evaluated in relation to disease risk; environmental factors are commonly understood to relate to macro ...
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A novel mutation in NDUFB11 unveils a new clinical phenotype associated with lactic acidosis and sideroblastic anemia [PDF]
, 2017 NDUFB11, a component of mitochondrial complex I, is a relatively small integral membrane protein, belonging to the 'supernumerary' group of subunits, but proved to be absolutely essential for the assembly of an active complex I.
Bertini, Enrico +21 more
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Molecular Phenotyping of Retinal Ganglion Cells [PDF]
The Journal of Neuroscience, 2002 Classifying all of the ganglion cells in the mammalian retina has long been a goal of anatomists, physiologists, and cell biologists. The rabbit retinal ganglion cell layer was phenotyped using intrinsic small molecule signals (aspartate, glutamate, glycine, glutamine, GABA, and taurine) and glutamate receptor-gated 1-amino-4-guanidobutane excitation ...
Robert E, Marc, Bryan W, Jones
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Comparative genome analysis of Wolbachia strain wAu [PDF]
, 2014 BACKGROUND: Wolbachia intracellular bacteria can manipulate the reproduction of their arthropod hosts, including inducing sterility between populations known as cytoplasmic incompatibility (CI). Certain strains have been identified that are unable to
Harris, Simon R. +3 more
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Frontiers in Genetics, 2015 Recent studies have implicated the role of differential co-expression or correlation structure in gene expression data to help explain phenotypic differences.
Caleb A Lareau +5 more
doaj +1 more source
Protein interactome of muscle invasive bladder cancer. [PDF]
PLoS ONE, 2015 Muscle invasive bladder carcinoma is a complex, multifactorial disease caused by disruptions and alterations of several molecular pathways that result in heterogeneous phenotypes and variable disease outcome.
Akshay Bhat +11 more
doaj +1 more source
Homeobox genes in normal and abnormal vasculogenesis [PDF]
, 2008 Homeobox containing genes are a family of transcription factors regulating normal development and controlling primary cellular processes (cell identity, cell division and differentiation) recently enriched by the discovery of their interaction with ...
Cantile M +3 more
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Molecular Evolution and the Phenotype [PDF]
Evolution, 1997 In terms of the acquisition of important and relevant data, molecular evolution is proceeding more rapidly than any other area of evolutionary biology. The reason is simple. Most of the data is produced by workers whose interest is in isolating and sequencing genes from their favorite organisms, without any particular interest in their evolution. These
John F. Y. Brookfield, Wen-Hsiung Li
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