Results 31 to 40 of about 1,740,047 (309)
A novel mutation in NDUFB11 unveils a new clinical phenotype associated with lactic acidosis and sideroblastic anemia [PDF]
, 2017 NDUFB11, a component of mitochondrial complex I, is a relatively small integral membrane protein, belonging to the 'supernumerary' group of subunits, but proved to be absolutely essential for the assembly of an active complex I.
Bertini, Enrico +21 more
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Scientific Reports, 2020 Autism spectrum disorder (ASD) is a continuum of neurodevelopmental disorders and needs new therapeutic approaches. Recently, oxytocin (OXT) showed potential as the first anti-ASD drug.
Machi Horiai +13 more
doaj +1 more source
Molecular Phenotypes of Atherosclerosis [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2004 The initiation and progression of atherosclerosis appears driven by a combination of genetic and environmental factors. Access to circulating lipoproteins or to molecules shed into the blood from arterial wall cells permits genetic diversity to be evaluated in relation to disease risk; environmental factors are commonly understood to relate to macro ...
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Molecular Phenotyping of Retinal Ganglion Cells [PDF]
The Journal of Neuroscience, 2002 Classifying all of the ganglion cells in the mammalian retina has long been a goal of anatomists, physiologists, and cell biologists. The rabbit retinal ganglion cell layer was phenotyped using intrinsic small molecule signals (aspartate, glutamate, glycine, glutamine, GABA, and taurine) and glutamate receptor-gated 1-amino-4-guanidobutane excitation ...
Robert E, Marc, Bryan W, Jones
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Protein interactome of muscle invasive bladder cancer. [PDF]
PLoS ONE, 2015 Muscle invasive bladder carcinoma is a complex, multifactorial disease caused by disruptions and alterations of several molecular pathways that result in heterogeneous phenotypes and variable disease outcome.
Akshay Bhat +11 more
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Frontiers in Genetics, 2015 Recent studies have implicated the role of differential co-expression or correlation structure in gene expression data to help explain phenotypic differences.
Caleb A Lareau +5 more
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Molecular Evolution and the Phenotype [PDF]
Evolution, 1997 In terms of the acquisition of important and relevant data, molecular evolution is proceeding more rapidly than any other area of evolutionary biology. The reason is simple. Most of the data is produced by workers whose interest is in isolating and sequencing genes from their favorite organisms, without any particular interest in their evolution. These
John F. Y. Brookfield, Wen-Hsiung Li
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Specific Preferences in Lineage Choice and Phenotypic Plasticity of Glioma Stem Cells Under BMP4 and Noggin Influence [PDF]
, 2015 Although BMP4-induced differentiation of glioma stem cells (GSCs) is well recognized, details of the cellular responses triggered by this morphogen are still poorly defined.
Arakaki, Naomi +10 more
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Sphingomyelin metabolism is involved in the differentiation of MDCK cells induced by environmental hypertonicity [PDF]
, 2015 Sphingolipids (SLs) are relevant lipid components of eukaryotic cells. Besides regulating various cellular processes, SLs provide the structural framework for plasma membrane organization.
Favale, Nicolas Octavio +4 more
core +1 more source
Mice doubly deficient in Six4 and Six5 show ventral body wall defects reproducing human omphalocele
Disease Models & Mechanisms, 2018 Omphalocele is a human congenital anomaly in ventral body wall closure and may be caused by impaired formation of the primary abdominal wall (PAW) and/or defects in abdominal muscle development.
Masanori Takahashi +3 more
doaj +1 more source