Results 121 to 130 of about 3,445,033 (308)

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Inferring kangaroo phylogeny from incongruent nuclear and mitochondrial genes [PDF]

, 2013
The marsupial genus Macropus includes three subgenera, the familiar large grazing kangaroos and wallaroos of M. (Macropus) and M. (Osphranter), as well as the smaller mixed grazing/browsing wallabies of M. (Notamacropus).
Pratt, R., Michael Bunce, Pratt, Ranae C., Haouchar, D., Renae C. Pratt, Phillips, M.J., Haouchar, D, Matthew J. Phillips, Dalal Haouchar, Gillian C. Gibb (270561), Renae C Pratt, Haouchar, Dalal, Pratt, R.C., Haouchar Dalal, Gibb, G., Gibb Gillian C., Gibb, Gillian, Phillips, M., Pratt Renae C., Matthew J Phillips, Michael Bunce (31164), Gillian C. Gibb, Gibb, G.C., Gillian C Gibb, Phillips Matthew J., Matthew J. Phillips (93244), Dalal Haouchar (381128), Renae C. Pratt (381129), Bunce, M., Bunce Michael, Phillips, Matthew J., Bunce, Michael   +31 more
core   +3 more sources

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Testing robustness of relative complexity measure method constructing robust phylogenetic trees for Galanthus L. Using the relative complexity measure [PDF]

, 2013
Background: Most phylogeny analysis methods based on molecular sequences use multiple alignment where the quality of the alignment, which is dependent on the alignment parameters, determines the accuracy of the resulting trees.
Sırrı Yüzbaşıoğlu, Taşçı Nivart, O Uğur Sezerman, Bakis, Yasin, Yuzbasioglu, Sirri, Neş’e Bilgin, Sezerman O Uğur, Cem Meydan, Yasin Bakış, Bakış Yasin, Sezerman, Uğur, Taşçı, Nivart, Bilgin, Nes'e, Bilgin, Neşe, Yüzbaşıoğlu, Sırrı, Meydan Cem, Bakış, Yasin, Otu Hasan H, Sezerman, O. Ugur, Meydan, Cem, Yüzbaşıoğlu Sırrı, Otu, Hasan H., Hasan H Otu, Nivart Taşçı, Tasci, Nivart, Bilgin Neş’e   +25 more
core   +1 more source

Phylogenomics and barcoding of Panax: toward the identification of ginseng species

BMC Evolutionary Biology, 2018
Background The economic value of ginseng in the global medicinal plant trade is estimated to be in excess of US$2.1 billion. At the same time, the evolutionary placement of ginseng (Panax ginseng) and the complex evolutionary history of the genus is ...
V. Manzanilla, A. Kool, L. Nguyen Nhat, H. Nong Van, H. Le Thi Thu, H. J. de Boer   +5 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

The complete mitochondrial genome and phylogenetic analysis of Leptobotia bellacauda (Teleostei: Cypriniformes: Botiidae)

Mitochondrial DNA. Part B. Resources
The complete mitochondrial genome of Leptobotia bellacauda was sequenced and characterized for the first time. The mitogenome was a 16,591 bp circular molecule, including 13 protein-coding genes (PCGs), 22 transfer RNA (tRNA) genes, two ribosomal RNA ...
YiJun Li, Xiaoge Yang, Mengqi Liao, Zhihua Zhong, Yuxi Lian   +4 more
doaj   +1 more source

Leveraging phytochemicals: the plant phylogeny predicts sources of novel antibacterial compounds

Future Science OA, 2019
Aim: The goal of this study was to use phylogenetic evidence to determine plant families with high representation of antibacterial activity and identify potential sources to focus on for antibacterial drug discovery. Materials & methods: We reconstructed
Malini A Prasad, Christine P Zolnik, Jeanmaire Molina   +2 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source