Results 121 to 130 of about 194,490 (314)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Inferring kangaroo phylogeny from incongruent nuclear and mitochondrial genes
, 2013 The marsupial genus Macropus includes three subgenera, the familiar large grazing kangaroos and wallaroos of M. (Macropus) and M. (Osphranter), as well as the smaller mixed grazing/browsing wallabies of M. (Notamacropus).
Pratt, R. +31 more
core +1 more source
A dated phylogeny and collection records reveal repeated biome shifts in the African genus Coccinia (Cucurbitaceae) [PDF]
, 2011 Background: Conservatism in climatic tolerance may limit geographic range expansion and should enhance the effects of habitat fragmentation on population subdivision.
Renner Susanne S +5 more
core +1 more source
Mitochondrial DNA. Part B. ResourcesThe complete mitochondrial genome of Leptobotia bellacauda was sequenced and characterized for the first time. The mitogenome was a 16,591 bp circular molecule, including 13 protein-coding genes (PCGs), 22 transfer RNA (tRNA) genes, two ribosomal RNA ...
YiJun Li +4 more
doaj +1 more source
Biogeographic history of the endangered dwarf buffalo, subgenus Anoa (Bovidae: Bubalus quarlesi and Bubalus depressicornis): a perspective based on mitochondrial DNA phylogeny [PDF]
Evolutionary SystematicsThe Anoa, including the Mountain Anoa (Bubalus quarlesi) and the Lowland Anoa (Bubalus depressicornis) according to current taxonomy, are endangered bovid species endemic to the tropical island of Sulawesi.
Dwi Sendi Priyono +3 more
doaj +3 more sources
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Phylogenomics and barcoding of Panax: toward the identification of ginseng species
BMC Evolutionary Biology, 2018 Background The economic value of ginseng in the global medicinal plant trade is estimated to be in excess of US$2.1 billion. At the same time, the evolutionary placement of ginseng (Panax ginseng) and the complex evolutionary history of the genus is ...
V. Manzanilla +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
From sea to land and beyond : new insights into the evolution of euthyneuran Gastropoda (Mollusca)
, 2008 Background The Euthyneura are considered to be the most successful and diverse group of Gastropoda. Phylogenetically, they are riven with controversy.
Annette Klussmann-Kolb +9 more
core +1 more source