Results 141 to 150 of about 6,351,992 (402)

Aging‐Driven Blood–Brain Barrier Dysfunction and Its Impact on CNS Cancer Susceptibility: A Comprehensive Narrative Review

open access: yesAging and Cancer, EarlyView.
Aging weakens the blood–brain barrier (BBB), increasing susceptibility to CNS cancers and complicating treatment. This review examines BBB deterioration, its impact on drug delivery, and potential interventions like targeting neuroinflammation and advanced therapies.
Quang La, Aiman Baloch, David F. Lo
wiley   +1 more source

A Python package for fast GPU‐based proton pencil beam dose calculation

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Open‐source GPU‐based Monte Carlo (MC) proton dose calculation algorithms provide high speed and unparalleled accuracy but can be complex to integrate with new applications and remain slower than GPU‐based pencil beam (PB) methods, which sacrifice some physical accuracy for sub‐second plan calculation.
Mahasweta Bhattacharya   +4 more
wiley   +1 more source

INTERACTIVE EDUCATIONAL TECHNOLOGIES IN THE COURSE "MOLECULAR PHYSICS"

open access: yesІнформаційні технології і засоби навчання, 2011
Teaching of general and special disciplines at physical faculty is impossible without a demonstration experiment, but not always the laboratory material resources correspond to the up-to-date level of a hardware.
Vitalij V. Grishchenko   +2 more
doaj  

Diffusion Models in $\textit{De Novo}$ Drug Design [PDF]

open access: yesarXiv
Diffusion models have emerged as powerful tools for molecular generation, particularly in the context of 3D molecular structures. Inspired by non-equilibrium statistical physics, these models can generate 3D molecular structures with specific properties or requirements crucial to drug discovery. Diffusion models were particularly successful at learning
arxiv  

An investigation into the feasibility and efficacy of stereotactic radiosurgery for 1–3 cm single brain lesions on the ring‐mounted Halcyon LINAC

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose An evaluation of the accuracy, safety, and efficiency of the Halcyon ring delivery system (RDS) for stereotactic radiosurgery (SRS) treatment to relatively small (1–3 cm) brain lesions. Methods After completing the extensive in‐house quality assurance checks including Winston–Lutz test and independent dose verification via MD Anderson ...
Kate Hazelwood   +5 more
wiley   +1 more source

Carrier-free Raman manipulation of trapped neutral atoms

open access: yesNew Journal of Physics, 2014
We experimentally realize an enhanced Raman control scheme for neutral atoms that features an intrinsic suppression of the two-photon carrier transition, but retains the sidebands which couple to the external degrees of freedom of the trapped atoms. This
René Reimann   +6 more
doaj   +1 more source

MolFusion: Multimodal Fusion Learning for Molecular Representations via Multi-granularity Views [PDF]

open access: yesarXiv
Artificial Intelligence predicts drug properties by encoding drug molecules, aiding in the rapid screening of candidates. Different molecular representations, such as SMILES and molecule graphs, contain complementary information for molecular encoding.
arxiv  

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