Phase 1, First‐In‐Human, Single‐/Multiple‐Ascending Dose Study of Iluzanebart in Healthy Volunteers
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of iluzanebart, a fully human monoclonal antibody TREM2 (triggering receptor expressed on myeloid cells 2) agonist, after single‐ (SAD) and multiple‐ascending‐dose (MAD) administration.
Andreas Meier +8 more
wiley +1 more source
Lavrentiev: Some Improperly Posed Problems of Math. Physics/Watson u. Nuttall: Topics in Several Particle Dynamics/Heim: Schaltungsalgebra/Magnus, Karrass und Solitar: Combinatorial Group Theory/Migdal: Theory of Finite Fermi Systems and Applications to Atomic Nuclei/Irodov: A Collection of Problems in Atomic & Nuclear Physics/IAEA: Photonuclear Reactions/Brown: Introduction to Electrical Discharges in Gases/Nozdrev: The Use of Ultrasonics in Molecular Physics/Sovran: Fluid Mechanics of … [PDF]
, 1968 K. Strubecker +13 more
openalex +1 more source
Universal Proteomic Signature After Exercise‐Induced Muscle Injury in Muscular Dystrophies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Several neuromuscular disorders (NMDs) are characterized by progressive muscle damage and are marked by the elevation of circulating muscle proteins from activity‐related injury. Despite a diverse array of genetic drivers, many NMDs share similar patterns of exercise intolerance and higher concentrations of muscle injury proteins ...
Mads G. Stemmerik +5 more
wiley +1 more source
Advancing Molecular Machine (Learned) Representations with Stereoelectronics-Infused Molecular Graphs [PDF]
arXivMolecular representation is a foundational element in our understanding of the physical world. Its importance ranges from the fundamentals of chemical reactions to the design of new therapies and materials. Previous molecular machine learning models have employed strings, fingerprints, global features, and simple molecular graphs that are inherently ...
arxiv
Fundamental principles of molecular physics [PDF]
American Journal of Sciencen ...
openaire +3 more sources
Molecular quantum electrodynamics in chemical physics [PDF]
, 2008 Casimir H. B. G. +11 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Objectives Ofatumumab, a fully human anti‐CD20 monoclonal antibody, is effective in reducing relapses and disability progression in patients with multiple sclerosis. This study aimed to examine immune profile changes associated with ofatumumab in a prospective cohort of Chinese patients with relapsing–remitting multiple ...
Shu Yang +9 more
wiley +1 more source
The Molecular Quantum electro-Dynamics Research Group in Budapest [PDF]
arXivThis article briefly overviews the scientific activities of the Molecular Quantum (electro-)Dynamics (MQD) Research Group in Budapest. Since its foundation in 2016, the MQD group has worked on molecular spectroscopy and molecular physics topics with primary applications and relevance to high-resolution and precision spectroscopy.
arxiv