Results 51 to 60 of about 1,191,748 (291)

Molecular Dynamics Simulations: Advances and Applications

open access: yesMolecules, 2022
Molecular dynamics (MD) simulations have led to great advances in many scientific disciplines, such as chemical physics, materials science, and biophysics [...]
Hugo A. L. Filipe, Luís M. S. Loura
doaj   +1 more source

Multiplex single‐cell profiling of putative cancer stem cell markers ALDH1, SOX9, SOX2, CD44, CD133 and CD15 in endometrial cancer

open access: yesMolecular Oncology, EarlyView.
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien   +7 more
wiley   +1 more source

Ten years older and no wiser

open access: yesCondensed Matter Physics, 2005
In a moment of madness, I wrote a summary of my life for the volume of Molecular Physics that noted my sixtieth anniversary. Evidently, I must have caused the editors of this issue some problems because in revenge they have requested that I write ...
D.Henderson
doaj   +1 more source

Correlation between fragility and free volume void size at glass transition temperature

open access: yesAIP Advances, 2022
Despite the tremendous endeavors devoted to exploiting the nature of glass transition, the factors that control the steepness index of viscosity near glass transition, that is, fragility, remain unclear.
Qingli Ma   +7 more
doaj   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi   +26 more
wiley   +1 more source

A study of New Physics searches with tritium and similar molecules

open access: yesEuropean Physical Journal C: Particles and Fields, 2020
Searches for New Physics focus either on the direct production of new particles at colliders or at deviations from known observables at low energies.
Wolfgang Gregor Hollik   +2 more
doaj   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Optical manipulation and assembly of micro/nanoscale objects on solid substrates

open access: yesiScience, 2022
Summary: Many light-based technologies have been developed to manipulate micro/nanoscale objects such as colloidal particles and biological cells for basic research and practical applications.
Jingang Li, Ali Alfares, Yuebing Zheng
doaj  

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

MARVEL Analysis of the Measured High-resolution Spectra of 12C16O

open access: yesThe Astrophysical Journal Supplement Series
The Measured Active Rotational–Vibrational Energy Levels (MARVEL) algorithm is used to determine accurate empirical rotational–vibrational energy levels for the ground electronic state of the diatomic ^12 C ^16 O molecule.
Salman Mahmoud   +9 more
doaj   +1 more source

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