Results 141 to 150 of about 1,920,958 (265)

New Functions of Mitochondrial Dysfunction in Gastric Cancer: From Molecular Processes to Potential Treatments. [PDF]

Int J Mol Sci
Liu H, Zhang Y, Wang J, Qiao M, Guo Q.
europepmc   +1 more source

Molecular Processes of Dodder Haustorium Formation on Host Plant under Low Red/Far Red (R/FR) Irradiation. [PDF]

Int J Mol Sci, 2022
Pan H, Li Y, Chen L, Li J.
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Random Functions as Data Compressors for Machine Learning of Molecular Processes. [PDF]

J Chem Theory Comput
Debnath J, Hummer G.
europepmc   +1 more source

Nanosecond Pulsed Electric Field Only Transiently Affects the Cellular and Molecular Processes of Leydig Cells. [PDF]

Int J Mol Sci, 2021
Kasprzycka W, Trębińska-Stryjewska A, Lewandowski RB, Stępińska M, Osuchowska PN, Dobrzyńska M, Achour Y, Osuchowski ŁP, Starzyński J, Mierczyk Z, Trafny EA.   +10 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

GSEA and the coexpression network approach identify novel pathway connections of molecular processes affected in Porto-sinusoidal vascular disease. [PDF]

PLoS One
Iyer A, Doornbos C, Evelo C, Kutmon M, Ehrhart F.   +4 more
europepmc   +1 more source

Plant Growth-Defense Trade-Offs: Molecular Processes Leading to Physiological Changes. [PDF]

Int J Mol Sci, 2021
Figueroa-Macías JP, García YC, Núñez M, Díaz K, Olea AF, Espinoza L.   +5 more
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Molecular Processes That Control Organic Electrosynthesis in Near-Electrode Microenvironments. [PDF]

J Am Chem Soc
Mathison R, Atwi R, McConnell HB, Ochoa E, Rani E, Akashige T, Röhr JA, Taylor AD, Avalos CE, Aydil ES, Rajput NN, Modestino MA.   +11 more
europepmc   +1 more source