Results 1 to 10 of about 10,169,709 (296)

A Multi‐Task Self‐Supervised Strategy for Predicting Molecular Properties and FGFR1 Inhibitors [PDF]

Advanced Science
Studying the molecular properties of drugs and their interactions with human targets aids in better understanding the clinical performance of drugs and guides drug development.
Xin Yang, Yang Wang, Ye Lin, Mingxuan Zhang, Ou Liu, Jianwei Shuai, Qi Zhao   +6 more
doaj   +2 more sources

Nipocalimab, an immunoselective FcRn blocker that lowers IgG and has unique molecular properties [PDF]

mAbs
Nipocalimab is a human immunoglobulin G (IgG)1 monoclonal antibody that binds to the neonatal Fc receptor (FcRn) with high specificity and high affinity at both neutral (extracellular) and acidic (intracellular) pH, resulting in the reduction of ...
Nilufer P. Seth, Rui Xu, Matthew DuPrie, Amit Choudhury, Samuel Sihapong, Steven Tyler, James Meador, William Avery, Edward Cochran, Thomas Daly, Julia Brown, Laura Rutitzky, Lynn Markowitz, Sujatha Kumar, Traymon Beavers, Sayak Bhattacharya, Hsin Chen, Viraj Parge, Karen Price, Yang Wang, Siddharth Sukumaran, Yvonne Pao, Katie Abouzahr, Fiona Elwood, Jay Duffner, Sucharita Roy, Pushpa Narayanaswami, Jonathan J. Hubbard, Leona E. Ling   +28 more
doaj   +2 more sources

Deposition of Chiral Heptahelicene Molecules on Ferromagnetic Co and Fe Thin-Film Substrates

Nanomaterials, 2022
The discovery of chirality-induced spin selectivity (CISS), resulting from an interaction between the electron spin and handedness of chiral molecules, has sparked interest in surface-adsorbed chiral molecules due to potential applications in spintronics,
Mohammad Reza Safari, Frank Matthes, Karl-Heinz Ernst, Daniel E. Bürgler, Claus M. Schneider   +4 more
doaj   +1 more source

Structural, Physicochemical and Thermal Properties of OSA-modified Waxy Maize Starch [PDF]

Kemija u Industriji, 2022
The aim of current work was to carry out a fine characterisation of the structural, physicochemical, and thermal properties of octenyl succinic anhydride (OSA)-modified waxy maize starch known under the marketed name Gel ‘N’ Melt™. Both Fourier transform
Amel Djori, Nadji Moulai-Mostefa
doaj   +1 more source

Effect of Exo/Endogenous Prophylaxis Dentifrice/Drug and Cariogenic Conditions of Patient on Molecular Property of Dental Biofilm: Synchrotron FTIR Spectroscopic Study

Pharmaceutics, 2022
(1) Objectives: This study is the first one to investigate the molecular composition of the dental biofilm during the exogenous and endogenous prophylaxis stages (use of dentifrice/drug) of individuals with different cariogenic conditions using molecular
Pavel Seredin, Dmitry Goloshchapov, Vladimir Kashkarov, Dmitry Nesterov, Yuri Ippolitov, Ivan Ippolitov, Jitraporn Vongsvivut   +6 more
doaj   +1 more source

Features of the molecular composition of dental biofilm in patients depending on the degree of caries and the method of its prevention: synchrotron FTIR spectroscopic studies

Конденсированные среды и межфазные границы, 2023
The article studies the molecular composition of dental biofilm in healthy people and patients with multiple caries lesions during several stages of exogenous and endogenous preventive measures.
Pavel V. Seredin, Dmitry L. Goloshchapov, Vladimir M. Kashkarov, Nikita S. Buylov, Yury A. Ippolitov, Ivan Yu. Ippolitov, Jitraporn (Pimm) Vongsvivut   +6 more
doaj   +1 more source

Quantification of the Properties of Organic Molecules Using Core‐Loss Spectra as Neural Network Descriptors

Advanced Intelligent Systems, 2022
Artificial neural networks are applied to quantify the properties of organic molecules by introducing a new descriptor, a core‐loss spectrum, which is typically observed experimentally using electron or X‐ray spectroscopy.
Kakeru Kikumasa, Shin Kiyohara, Kiyou Shibata, Teruyasu Mizoguchi   +3 more
doaj   +1 more source

Hydrophobicity Enhances the Formation of Protein-Stabilized Foams

Molecules, 2022
Screening proteins for their potential use in foam applications is very laborious and time consuming. It would be beneficial if the foam properties could be predicted based on their molecular properties, but this is currently not possible.
Roy J. B. M. Delahaije, Peter A. Wierenga   +1 more
doaj   +1 more source

Thermal Bioprinting Causes Ample Alterations of Expression of LUCAT1, IL6, CCL26, and NRN1L Genes and Massive Phosphorylation of Critical Oncogenic Drug Resistance Pathways in Breast Cancer Cells

Frontiers in Bioengineering and Biotechnology, 2020
Bioprinting technology merges engineering and biological fields and together, they possess a great translational potential, which can tremendously impact the future of regenerative medicine and drug discovery.
Aleli Campbell, Jonathon E. Mohl, Denisse A. Gutierrez, Armando Varela-Ramirez, Thomas Boland   +4 more
doaj   +1 more source

Theoretical Study of Reactions with Electrophones Substitutions: by B3lyp-Dft Density Function Calculation [PDF]

Engineering and Technology Journal, 2014
Density functional theory (DFT), using the B3LYP functional was utilized to study the molecular properties (benzene molecule was a reference) of 1,3,5-Trihydroxybenzene (THB) compound in order to determine the relationship between molecular structure and
Rashed Taleb Rasheed, Hadeel Salah Mansoor, Aseel Salah Mansoor, Emad A. Yousif   +3 more
doaj   +1 more source