Results 251 to 260 of about 813,980 (316)

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

On-Surface Molecular Recognition Driven by Chalcogen Bonding. [PDF]

JACS Au
Camilli L, Hogan C, Romito D, Persichetti L, Caporale A, Palummo M, Di Giovannantonio M, Bonifazi D.   +7 more
europepmc   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Molecular recognition and potentiometric determination of neostigmine and pyridostigmine by a methylene-bridged naphthotube. [PDF]

RSC Adv
Wu JF, Chen WJ, Wang LL, Yang LP, Wang YF, Liao D.   +5 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Author Correction: Accurate molecular recognition from the lowest unoccupied molecular orbital. [PDF]

Sci Rep
Zhou X, Yang S, Han C.
europepmc   +1 more source

Theoretical insight and molecular recognition of fluconazole molecularly imprinted polymers: a combined computational and experimental analysis. [PDF]

RSC Adv
Gunawan U, Ibrahim S, Ivansyah AL, Damayanti S.   +3 more
europepmc   +1 more source

Bulk transparent supramolecular glass enabled by host-guest molecular recognition. [PDF]

Nat Commun
Cai C, Wu S, Zhang Y, Li F, Tan Z, Dong S.   +5 more
europepmc   +1 more source

Molecular recognition of an odorant by the murine trace amine-associated receptor TAAR7f. [PDF]

Nat Commun
Gusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Veprintsev DB, Vaidehi N, Weyand SN, Tate CG.   +14 more
europepmc   +1 more source

Development of A Novel EvaGreen-Dye Based Recombinase Aided Amplification Assay Using Self-Avoiding Molecular Recognition System Primers. [PDF]

China CDC Wkly
Shen X, Hua S, Zhao Z, Tian F, Li L, Ma X.   +5 more
europepmc   +1 more source