Results 1 to 10 of about 602,330 (313)

Matrix-Mediated Delivery of Silver Nanoparticles for Prevention of Staphylococcus aureus and Pseudomonas aeruginosa Biofilm Formation in Chronic Rhinosinusitis

Pharmaceutics, 2023
Chronic rhinosinusitis (CRS) is a chronic health condition affecting the sinonasal cavity. CRS-associated mucosal inflammation leads to sinonasal epithelial cell death and epithelial cell barrier disruption, which may result in recurrent bacterial ...
Bhuvanesh Yathavan, Tanya Chhibber, Douglas Steinhauff, Abigail Pulsipher, Jeremiah A. Alt, Hamidreza Ghandehari, Paris Jafari   +6 more
doaj   +1 more source

Neonatal NET-Inhibitory Factor improves survival in the cecal ligation and puncture model of polymicrobial sepsis by inhibiting neutrophil extracellular traps

Frontiers in Immunology, 2023
IntroductionNeutrophil extracellular traps (NETs) clear pathogens but may contribute Q8 pathogenically to host inflammatory tissue damage during sepsis.
Claudia V. de Araujo, Claudia V. de Araujo, Frederik Denorme, W. Zac Stephens, Qing Li, Mark J. Cody, Mark J. Cody, Jacob L. Crandell, Aaron C. Petrey, Aaron C. Petrey, Kimberly A. Queisser, Kimberly A. Queisser, John L. Rustad, James M. Fulcher, Judah L. Evangelista, Michael S. Kay, Joshua D. Schiffman, Joshua D. Schiffman, Robert A. Campbell, Robert A. Campbell, Christian C. Yost, Christian C. Yost   +21 more
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NHR-14 loss of function couples intestinal iron uptake with innate immunity in C. elegans through PQM-1 signaling

eLife, 2019
Iron is essential for survival of most organisms. All organisms have thus developed mechanisms to sense, acquire and sequester iron. In C. elegans, iron uptake and sequestration are regulated by HIF-1.
Malini Rajan, Cole P Anderson, Paul M Rindler, Steven Joshua Romney, Maria C Ferreira dos Santos, Jason Gertz, Elizabeth A Leibold   +6 more
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Crystal structure and Hirshfeld surface analysis of the hydrochloride salt of 8-{4-[(6-phenylpyridin-3-yl)methyl]piperazin-1-yl}-3,4-dihydroquinolin-2(1H)-one

Acta Crystallographica Section E: Crystallographic Communications, 2021
The amine 8-{4-[(6-phenylpyridin-3-yl)methyl]piperazin-1-yl}-3,4-dihydroquinolin-2(1H)-one was crystallized as the hydrochloride salt, 4-(2-oxo-1,2,3,4-tetrahydroquinolin-8-yl)-1-[(6-phenylpyridin-3-yl)methyl]piperazin-1-ium chloride, C25H27N4+·Cl− (I ...
Nisar Ullah, Helen Stoeckli-Evans
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FOXN3 controls liver glucose metabolism by regulating gluconeogenic substrate selection

Physiological Reports, 2019
The FOXN3 gene locus is associated with fasting blood glucose levels in non‐diabetic human population genetic studies. The blood glucose‐modifying variation within this gene regulates the abundance of both FOXN3 protein and transcript in primary human ...
Santhosh Karanth, Bhagirath Chaurasia, Faith M. Bowman, Trevor S. Tippetts, William L. Holland, Scott A. Summers, Amnon Schlegel   +6 more
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2-Aminoanilinium benzene-1,2-diaminium tris(4-methylbenzene-1-sulfonate)

IUCrData, 2018
In the title molecular salt, C6H10N22+·C6H9N2+·3C7H7O3S−, one of the cations is doubly protonated and one is singly protonated with charge balance achieved by three sulfonate anions. The crystal packing features N—H...O and C—H...O hydrogen bonds.
C. Amirthakumar, P. Pandi, R. Mohan Kumar, G. Chakkaravarthi   +3 more
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1H-Benzo[d]imidazol-3-ium (Z)-3-carboxyprop-2-enoate

IUCrData, 2016
In the anion of the title molecular salt, C7H7N2+.C4H3O4−, an O—H...O hydrogen bond generates an S(7) graph-set motif while a pair of intermolecular N—H...O and C—H...O hydrogen bonds generate an R44(10) ring-motif.
M. Amudha, B. Gunasekaran, P. Praveen Kumar, G. Chakkaravarthi   +3 more
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Crystal structure of (4-methoxyphenyl)[(4-methoxyphenyl)phosphonato]dioxidophosphate(1−) 2-amino-6-benzyl-3-ethoxycarbonyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-6-ium

Acta Crystallographica Section E: Crystallographic Communications, 2015
The asymmetric unit of the title molecular salt, C17H21N2O2S+·C14H15O7P2−, comprises two cations and two anions. Each cation features an intramolecular N—H...O hydrogen bond, which closes an S(6) ring; in each case the hydropyridine ring adopts a half ...
Joel T. Mague, Shaaban K. Mohamed, Mehmet Akkurt, Sabry H. H. Younes, Essam K. Ahmed, Mustafa R. Albayati   +5 more
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Piperazine-1,4-diium bis(4-nitrobenzoate) dihydrate

IUCrData, 2017
The asymmetric unit of the title molecular salt, C4H12N22+·2C7H4NO4− ·2H2O, is composed of half a protonated piperazine dication, located about an inversion center, a benzoate anion and a water molecule of crystallization.
R. Rajkumar, P. Praveen Kumar, B. Gunasekaran   +2 more
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4-Methylpyridinium 2-carboxy-6-nitrobenzoate

IUCrData, 2016
In the title molecular salt, C6H8N+·C8H4NO6−, the anion is deprotonated at the carboxylic acid group adjacent to the nitro group. In the crystal, the anions are linked into an [001] chain by O—H...O hydrogen bonds.
S. Reena Devi, S. Kalaiyarasi, R. Akilan, R. Mohan Kumar, G. Chakkaravarthi   +4 more
doaj   +1 more source