Results 201 to 210 of about 1,833,643 (261)

User Guided Selection and Alignment of Sequence Data by GeneMatrix. [PDF]

J Mol Evol
Goodman SJ, Carr IM.
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Re: "A novel splice-altering frameshift variant in the COL1A1 gene underlies osteogenesis imperfecta type I: molecular characterization of a four-generation Chinese pedigree and literature review". [PDF]

Hum Genomics
Dalgleish R.
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Rethinking bioinformatics in liquid-liquid phase separation: data resources, predictive models, and an event-centric perspective. [PDF]

Brief Bioinform
Yuan ZL, Wang B, Chen YL, Huang HQ, Li BH, Zahoor A, Ren L, Du M, Fang RQ, Ning L.   +9 more
europepmc   +1 more source

Structural characterization of the human CC2D1A fragment associated with non-syndromic intellectual disability (NSID). [PDF]

Biosci Rep
Yeh YH, Lin MG, Sun XH, Shen YY, Ling P, Hsiao CD.   +5 more
europepmc   +1 more source

MDNA : a software module for DNA structure generation and analysis. [PDF]

Nucleic Acids Res
van Heesch T, Skoruppa E, Bolhuis PG, Schiessel H, Vreede J.   +4 more
europepmc   +1 more source

Complete plastome data of rare <i>Allium microdictyon</i>, an edible and medicinally important wild onion from the Kazakhstan Altay. [PDF]

Data Brief
Almerekova S, Ibraimov A, Yermagambetova M, Abugalieva S, Turuspekov Y.   +4 more
europepmc   +1 more source

BeeGees: A High-Throughput Protein-Coding DNA Barcode Recovery Pipeline Tailored for Genome Skims of Museum Specimens. [PDF]

Mol Ecol Resour
Parsons DAJ, Vos RA, Price BW.
europepmc   +1 more source