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Evolutionary analysis of molecular sequence data
2007Abstract In the 140 years since Darwin’s Origin of Species was published, evolutionary ideas have formed an important part of the theoretical framework of biological research, but their practical consequences have been few for most of that period.
Hughes, A., Da Silva, J., Verra, F.
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Molecular Epidemiology Database for Sequence Management and Data Mining
2017A central database to aggregate sequence information from a range of epidemiological aspects including HTLV-1 pathogenesis, origin, and evolutionary dynamic would be useful to scientists and physicians worldwide. This Chapter describes two online tools for studies related to HTLV-1, the HTLV-1 Molecular Epidemiology Database and the HTLV-1 Subtyping ...
Thessika Hialla Almeida, Araújo +2 more
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Fixed Character States and the Optimization of Molecular Sequence Data
Cladistics, 1999A method is proposed to optimize molecular sequence data that does not employ multiple sequence alignment. This method treats entire homologous contiguous stretches of sequence data as individual characters. This sequence is treated as the homologous unit employed in phylogeny reconstruction.
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Analysis of recombination in molecular sequence data
2008Wir präsentieren Recco, eine neue und schnelle Methode zur Analyse von Rekombinationen in multiplen Alignments. Recco basiert auf einem dynamischen Programm, welches eine Sequenz im Alignment durch die anderen Sequenzen im Alignment rekonstruiert, wobei die Operatoren Mutation und Rekombination erlaubt sind.
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Quantitation of Molecular Pathway Activation Using RNA Sequencing Data
2019Intracellular molecular pathways (IMPs) control all major events in the living cell. IMPs are considered hotspots in biomedical sciences and thousands of IMPs have been discovered for humans and model organisms. Knowledge of IMPs activation is essential for understanding biological functions and differences between the biological objects at the ...
Nicolas, Borisov +3 more
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Pattern Recognition, 1993
Abstract The notion of probabilistic consensus structure, a probabilistic model satisfying certain domain constraints, is defined as a statistical relational graph inferred from an ensemble of sequences (or strings). The probabilistic consensus structure is a special form of random graph indicating both the statistical variation and the structural ...
David K. Y. Chiu, George Harauz
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Abstract The notion of probabilistic consensus structure, a probabilistic model satisfying certain domain constraints, is defined as a statistical relational graph inferred from an ensemble of sequences (or strings). The probabilistic consensus structure is a special form of random graph indicating both the statistical variation and the structural ...
David K. Y. Chiu, George Harauz
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Bayesian Hypothesis Testing of Four-Taxon Topologies Using Molecular Sequence Data
Biometrics, 1996The reconstruction of phylogenetic trees from molecular sequences presents unusual problems for statistical inference. For example, three possible alternatives must be considered for four taxa when inferring the correct unrooted tree (referred to as a topology).
Sinsheimer, Janet S. +2 more
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Short Introduction to Phylogenetic Analysis of Molecular Sequence Data
2018Phylogeny is a model of the relationships between organisms, genes, protein, and other structures based on common ancestry. It is also used for epidemiological investigations and analysis of parallel evolution between host and parasite. Phylogenetic trees can be visualized as dendrograms or as radial trees.
Henrik Christensen, John Elmerdahl Olsen
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Estimation of Divergence Times from Molecular Sequence Data
2005“A comparison of the structures of homologous proteins (i.e., proteins with the same kinds of biological activity or function) from different species is important, therefore, for two reasons. First, the similarities found give a measure of the minimum structure for biological function.
Jeffrey L. Thorne, Hirohisa Kishino
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Data Encryption Using Zigzag and Sequences of Bio Molecular Information
Indian Journal of Public Health Research & Development, 2019This paper proposed a new encryption algorithm for secure file communication. It consists of three stages of protection: DNA computation, generating keys, and encryption. The first stage, the file is converted to protein sequences. The second stage, an enormous number of random keys are generated of length ranged from (2^8 to 2^512 bits) using mRNA and
Rasha S. Ali +2 more
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