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Quantitation of Molecular Pathway Activation Using RNA Sequencing Data
2019Intracellular molecular pathways (IMPs) control all major events in the living cell. IMPs are considered hotspots in biomedical sciences and thousands of IMPs have been discovered for humans and model organisms. Knowledge of IMPs activation is essential for understanding biological functions and differences between the biological objects at the ...
Nicolas, Borisov +3 more
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Pattern Recognition, 1993
Abstract The notion of probabilistic consensus structure, a probabilistic model satisfying certain domain constraints, is defined as a statistical relational graph inferred from an ensemble of sequences (or strings). The probabilistic consensus structure is a special form of random graph indicating both the statistical variation and the structural ...
David K. Y. Chiu, George Harauz
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Abstract The notion of probabilistic consensus structure, a probabilistic model satisfying certain domain constraints, is defined as a statistical relational graph inferred from an ensemble of sequences (or strings). The probabilistic consensus structure is a special form of random graph indicating both the statistical variation and the structural ...
David K. Y. Chiu, George Harauz
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Short Introduction to Phylogenetic Analysis of Molecular Sequence Data
2018Phylogeny is a model of the relationships between organisms, genes, protein, and other structures based on common ancestry. It is also used for epidemiological investigations and analysis of parallel evolution between host and parasite. Phylogenetic trees can be visualized as dendrograms or as radial trees.
Henrik Christensen, John Elmerdahl Olsen
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Bayesian Hypothesis Testing of Four-Taxon Topologies Using Molecular Sequence Data
Biometrics, 1996The reconstruction of phylogenetic trees from molecular sequences presents unusual problems for statistical inference. For example, three possible alternatives must be considered for four taxa when inferring the correct unrooted tree (referred to as a topology).
Sinsheimer, Janet S. +2 more
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Estimation of Divergence Times from Molecular Sequence Data
2005“A comparison of the structures of homologous proteins (i.e., proteins with the same kinds of biological activity or function) from different species is important, therefore, for two reasons. First, the similarities found give a measure of the minimum structure for biological function.
Jeffrey L. Thorne, Hirohisa Kishino
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Data Encryption Using Zigzag and Sequences of Bio Molecular Information
Indian Journal of Public Health Research & Development, 2019This paper proposed a new encryption algorithm for secure file communication. It consists of three stages of protection: DNA computation, generating keys, and encryption. The first stage, the file is converted to protein sequences. The second stage, an enormous number of random keys are generated of length ranged from (2^8 to 2^512 bits) using mRNA and
Rasha S. Ali +2 more
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A method for molecular phylogeny construction by direct use of nucleotide sequence data
Journal of Molecular Evolution, 1990A method for molecular phylogeny construction is newly developed. The method, called the stepwise ancestral sequence method, estimates molecular phylogenetic trees and ancestral sequences simultaneously on the basis of parsimony and sequence homology. For simplicity the emphasis is placed more on parsimony than on sequence homology in the present study,
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The role of internal node sequences and the molecular clock in the analysis of serially-sampled data
International Journal of Bioinformatics Research and Applications, 2008Algorithms that infer phylogenetic relationships between serially-sampled sequences have been developed in recent years to assist in the analysis of rapidly-evolving human pathogens. Our study consisted of evaluating seven relevant methods using empirical as well as simulated data sets.
Patricia Buendia +2 more
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Reconstruction of molecular phylogeny of extant hominoids from DNA sequence data
American Journal of Physical Anthropology, 1991AbstractEvolutionary distance matrices of the extant hominoids are computed from DNA sequence data, and hominoid DNA phylogenies are reconstructed by applying the neighbor‐joining method to these distance matrices. The chimpanzee is clustered with the human in most of the phylogenetic trees thus obtained.
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Molecular Systematics of the Trilliaceae sensu lato as Inferred from rbcL Sequence Data
Molecular Phylogenetics and Evolution, 1995In this paper, we examine the phylogenetic affinities of Trilliaceae sensu lato. DNA sequences of the rbcL gene were analyzed for 8 species from Trilliaceae sensu lato (Trillium kamtschaticum, T. sessile, Daiswa polyphylla, Kinugasa japonica, Paris tetraphylla, Scoliopus bigelovii, S.
H, Kato +3 more
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