Results 281 to 290 of about 4,241,168 (373)

FIGURE 6 in Two new Docosia Winnertz species (Diptera: Mycetophilidae) from Transcaucasia, with DNA sequence data and updated molecular phylogeny

Kurina, Olavi, Burdíková, Nikola, Ševčík, Jan   +2 more
openalex   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

BAGEL: Protein engineering via exploration of an energy landscape. [PDF]

PLoS Comput Biol
Lála J, Al-Saffar A, Angioletti-Uberti S.   +2 more
europepmc   +1 more source

FIGURE 3 in Two new Docosia Winnertz species (Diptera: Mycetophilidae) from Transcaucasia, with DNA sequence data and updated molecular phylogeny

Kurina, Olavi, Burdíková, Nikola, Ševčík, Jan   +2 more
openalex   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Cloning of <i>PoAIL6</i> Gene Related to Somatic Embryogenesis in <i>Paeonia ostii</i> 'Fengdan'. [PDF]

Int J Mol Sci
Chang Y, Zhang X, Deng Y, Hu T, Jiang Z, Zhang W.   +5 more
europepmc   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

The Emergence of a CRISPR-Cas Revolution in Ecology: Applications, Challenges, and an Ecologist's Overview of the Toolbox. [PDF]

Mol Ecol Resour
Plewnia A, Hoenig BD, Lötters S, Heine C, Erens J, Böning P, Bending GD, Krehenwinkel H, Williams MA.   +8 more
europepmc   +1 more source

Cloning, expression, purification, and structural modeling of the Chandipura virus matrix protein

FEBS Open Bio, EarlyView.
This research protocol offers a guide for the cloning, expression, and purification of the Chandipura virus matrix protein using E. coli. It also includes a step‐by‐step procedure for cloning, expressing, and conducting fluorescence imaging of GFP‐fused Chandipura virus matrix protein in mammalian cell lines.
Mariana Grieben
wiley   +1 more source

Structural phylogenetics unravels the evolutionary diversification of communication systems in gram-positive bacteria and their viruses. [PDF]

Nat Struct Mol Biol
Moi D, Bernard C, Steinegger M, Nevers Y, Langleib M, Dessimoz C.   +5 more
europepmc   +1 more source