Results 111 to 120 of about 19,367,956 (387)

NONEXPERIMENTAL SCREENING OF THE WATER SOLUBILITY, LIPOPHILICITY, BIOAVAILABILITY, MUTAGENICITY AND TOXICITY OF VARIOUS PESTICIDES WITH QSAR MODELS AID [PDF]

Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2013
In our study the dataset containing 489 pesticides and their active substances of different classes of organic compounds was used for analysis. For compounds of analyzed dataset the values of lipophilicity, water solubility, toxicity, bioavailability and
O.G. Kolumbin, L.N. Ognichenko, A.G. Artemenko, P.G. Polischuk, М.A. Kulinsky, Е.N. Мuratov, V.E. Kuz’min, V.A. Bobeica   +7 more
doaj  

Spiral shocks and the formation of molecular clouds in a two phase medium

, 2007
We extend recent numerical results (Dobbs et. al. 2006) on molecular cloud formation in spiral galaxies by including a multi-phase medium. The addition of a hot phase of gas enhances the structure in the cold gas, and significantly increases the fraction
Allen, Audit, Bate, Benz, Bergin, Blitz, Bonnell, Bonnell, C. L. Dobbs, Cox, Cox, Dobbs, Dobbs, Engargiola, Gibson, Gibson, Gittins, Glover, Glover, Heitsch, Heyer, I. A. Bonnell, Kaufman, Kim, Kim, Klaassen, Le Petit, Lequeux, Mac Low, Monaghan, Monaghan, Ostriker, Piontek, Pringle, Solomon, Thacker, Vazquez-Semadeni, Vazquez-Semadeni, Vogel, Wada, Wada, Wada, Williams, Williams, Wolfire   +44 more
core   +2 more sources

Purification tags markedly affect self‐aggregation of CPEB3

FEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito, Yujin Lee, Motoharu Ueno, Naotaka Sekiyama, Masatomo So, Ayako Furukawa, Kenji Sugase   +6 more
wiley   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Decoding temporal thermogenesis: coregulator selectivity and transcriptional control in brown and beige adipocytes

Adipocyte
In mammals, brown adipose tissue (BAT) and beige adipocytes in white adipose tissue (WAT) play pivotal roles in maintaining body temperature and energy metabolism.
Yong Geun Jeon, Sun Won Kim, Jae Bum Kim
doaj   +1 more source

Molecular structure of bottlebrush polymers in melts

Science Advances, 2016
Steric repulsion between grafted side chains inhibits interpenetration of bottlebrushes, transforming them into flexible filaments. Bottlebrushes are fascinating macromolecules that display an intriguing combination of molecular and particulate features ...
J. Paturej, S. Sheiko, Sergey Vladimir Panyukov, M. Rubinstein   +3 more
semanticscholar   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

Spectroscopic-network-assisted precision spectroscopy and its application to water

Nature Communications, 2020
Precision-spectroscopy techniques can accurately measure lines in constrained frequency and intensity ranges. The authors propose a spectroscopic-network-assisted precision spectroscopy method by which transitions measured in a narrow range provide ...
Roland Tóbiás, Tibor Furtenbacher, Irén Simkó, Attila G. Császár, Meissa L. Diouf, Frank M. J. Cozijn, Joey M. A. Staa, Edcel J. Salumbides, Wim Ubachs   +8 more
doaj   +1 more source

CS, HC3N and CH3CCH multi-line analyses towards starburst galaxies. The evolution of cloud structures in the central regions of galaxies

, 2010
We aim to study the properties of the dense molecular gas towards the inner few 100 pc of four nearby starburst galaxies dominated both by photo dissociation regions (M82) and large-scale shocks (NGC253, IC342 and Maffei2), and to relate the chemical and
Aladro, Rebeca, Bayet, Estelle, Martin, Sergio, Martin-Pintado, Jesus, Mauersberger, Rainer   +4 more
core   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source