Results 121 to 130 of about 11,784,011 (316)

Supramolecular complex formed by DNA oligonucleotide and thiacalix[4]arene. NMR-spectroscopy and molecular docking [PDF]

, 2014
The combination of NMR-spectroscopy and molecular docking was applied to investigate the complexation of thiacalix[4]arene with DNA. We have studied the structure of supramolecular complex formed by palindromic decamer DNA d(GCGTTAACGC)2 and ...
Khairutdinov B., Ermakova E., Zuev Y., Stoikov I., Sitnitsky A.   +4 more
core  

A tellurium-based cathepsin B inhibitor: Molecular structure, modelling, molecular docking and biological evaluation

, 2012
The crystallographically determined structure of biologically active 4,4-dichloro-1,3-diphenyl-4-telluraoct-2-en-1-one, 3, shows the coordination geometry for Te to be distorted psi-pentagonal bipyramidal based on a C2OCl3(lone pair) donor set.
José G.S. Lopes, Edward R.T. Tiekink, Maria H.S. Cezari, Rodrigo L.O.R. Cunha, Caracelli, Ignez, Cezari, Maria H. S., Cunha, Rodrigo L. O. R., João V. Comasseto, Luiz Juliano, Mauricio Vega-Teijido, Vega-Teijido, Mauricio [UNESP], Comasseto, Joao Valdir, Vega-Teijido, Mauricio, Juliano, Luiz, Paulo S. Santos, Julio Zukerman-Schpector, Santos, Paulo S., Cunha, Rodrigo L. O. R. [UNIFESP], Santos, Paulo Sergio, Lopes, Jose G. S., Cezari, Maria H. S. [UNIFESP], Zukerman-Schpector, Julio, Juliano, Luiz [UNIFESP], Ignez Caracelli, Comasseto, Joao V., Tiekink, Edward R. T.   +25 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Targeted Stimulation of Micropores by CS2 Extraction on Molecular of Coal [PDF]

The targeted stimulation of micropores based on the transformation of coal’s molecular structure is proposed due to the chemical properties and difficult-to-transform properties of micropores.
Zhen Zhang, Liu, Gaofeng, Barakos, George, Jia Lin, Ping Chang, Lin, Jia, Zhang, Zhen, George Barakos, Chang, Ping, Wang, Xiaoming, Xiaoming Wang, Gaofeng Liu   +11 more
core   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

The University of Chicago Department of Physics Laboratory of Molecular Structure and Spectra Technical Report for the Period 1 April 1951 to 31 March 1952: Part One

, 1952
Report containing articles, manuscripts, and tabulations of recorded spectra created by the Spectroscopic Laboratory of the University of ...
University of Chicago. Laboratory of Molecular Structure and Spectra.
core  

The effect of guest molecules on the conformation and molecular assembly of the fac-[RuCl3(NO)(dppb)] complex

, 2013
This paper describes the occurrence of two crystalline solvate forms of the nitrosyl ruthenium complex fac-[RuCl3(NO)(dppb)] (dppb = 1,4-bis(diphenylphosphino)butane), and the role of acetone and chloroform inclusions on molecular conformations and ...
Ellena, Javier, Batista, Alzir A., Corrêa, Rodrigo S., Barolli, João P., Barbosa, Marília I. F.   +4 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Structure-property relationship of 3-(N-phthalimidomethyl)-4-amino-1,2,4-triazole-5-thione: A structural, spectroscopic and DFT study

, 2017
The title molecule, 3-(N-phthalimidomethyl)-4-amino-1,2,4-triazole-5-thione (C11H9N5O2S), was synthesized by the fusion of N-Phthaloylglycine and thiocarbohydrazide at 145 degrees C.
Avcı, Davut, Atalay, Yusuf, Rumana Quershi, Azra Yaqub, Tamer, Ömer, Moazzam H. Bhatti, Uzma Yunus, Muhammad Nadeem   +7 more
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source