Results 231 to 240 of about 19,935,117 (378)

Insights on the structure and properties of sodium iron phosphate glasses from molecular dynamics simulations

open access: green
Jayani Kalahe   +5 more
openalex   +2 more sources

Production of antibacterial compounds by a Steely hybrid polyketide synthase in Dictyostelium

open access: yesFEBS Open Bio, EarlyView.
By selecting appropriate production species under optimised culture conditions, new chlorinated dibenzofuran compounds, which previously could not be analysed in sufficient quantities, were identified from cellular slime mould fruiting bodies. The strong antibacterial activity exhibited by these compounds suggests a link to the ecological function of ...
Tomoaki R. Yamashita   +3 more
wiley   +1 more source

The Molecular Structures of Methane [PDF]

open access: yesProceedings of the National Academy of Sciences, 1928
openaire   +2 more sources

Molecular Structure of the Human CFTR Ion Channel

open access: yesCell, 2017
Fangyu Liu   +4 more
semanticscholar   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

open access: yesFEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama   +7 more
wiley   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

open access: yesFEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Molecular structure of diisopropyl sulfide as determined by gas electron diffraction.

open access: bronze, 1986
Hiroyuki Kondo   +3 more
openalex   +2 more sources

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

open access: yesFEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez   +5 more
wiley   +1 more source

13C-Labelled Folates as NMR Probes of the Binding of Folate to Bacterial Dihydrofolate Reductases

open access: yesPteridines, 1991
Cheung H. T. A.   +4 more
doaj   +1 more source

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