Results 261 to 270 of about 19,935,117 (378)

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

VTX: real-time high-performance molecular structure and dynamics visualization software. [PDF]

open access: yesBioinformatics
Maria M   +12 more
europepmc   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

Molecular Structure and Thermodynamics of CO<sub>2</sub> and Water Adsorption on Mica. [PDF]

open access: yesJ Phys Chem B
Aybar M   +6 more
europepmc   +1 more source

1091 Decoding clinical and molecular determinants of tertiary lymphoid structure heterogeneity in pancreatic cancer by integrating multimodal spatial transcriptomics, proteomics, and histopathology imaging [PDF]

open access: hybrid
Michael J. Geuenich   +12 more
openalex   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

open access: yesFEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Molecular Structure of Omniphobic, Surface-Grafted Polydimethylsiloxane Chains. [PDF]

open access: yesSmall
Khatir B   +10 more
europepmc   +1 more source

Molecular markers reveal that population structure of the human pathogen Candida albicans exhibits both clonality and recombination.

open access: green, 1996
Yvonne Gräser   +6 more
openalex   +2 more sources

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