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Hidden burden of malaria in pregnancy in hard-to-reach areas of Odisha, India: challenges to elimination and the case for integrating molecular surveillance [PDF]

open access: yesFrontiers in Public Health
BackgroundMalaria in pregnancy (MiP) remains a major public health concern due to its detrimental effects on maternal and foetal health, posing a substantial challenge to malaria control and elimination efforts. Asymptomatic/Sub-patent malaria infections,
Sonali Sandeepta   +11 more
doaj   +2 more sources

Respiratory Syncytial Virus: New Challenges for Molecular Epidemiology Surveillance and Vaccination Strategy in Patients with ILI/SARI

open access: yesVaccines, 2021
Several respiratory pathogens are responsible for influenza-like illness (ILI) and severe respiratory infections (SARI), among which human respiratory syncytial virus (hRSV) represents one of the most common aetiologies.
Fabio Tramuto   +11 more
doaj   +3 more sources

Molecular Epidemiology Surveillance of SARS-CoV-2: Mutations and Genetic Diversity One Year after Emerging

open access: yesPathogens, 2021
In December 2019, the first cases of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were identified in the city of Wuhan, China. Since then, it has spread worldwide with new mutations being reported.
Alejandro Flores-Alanis   +7 more
doaj   +3 more sources

From Clinical Specimen to Whole Genome Sequencing of A(H3N2) Influenza Viruses: A Fast and Reliable High-Throughput Protocol

open access: yesVaccines, 2022
(1) Background: Over the last few years, there has been growing interest in the whole genome sequencing (WGS) of rapidly mutating pathogens, such as influenza viruses (IVs), which has led us to carry out in-depth studies on viral evolution in both ...
Cristina Galli   +10 more
doaj   +1 more source

Methicillin-Resistant Staphylococcus aureus (MRSA) Clonal Replacement in a Malaysian Teaching Hospital: Findings from an Eight-Year Interval Molecular Surveillance

open access: yesAntibiotics, 2021
Periodical surveillance on nosocomial pathogens is important for antimicrobial stewardship and infection control. The first methicillin-resistant Staphylococcus aureus (MRSA) molecular surveillance in Hospital Canselor Tuanku Muhriz (HCTM), a Malaysian ...
Mohd Azrul Hisham Ismail   +6 more
doaj   +1 more source

Decentralized Investigation of Bacterial Outbreaks Based on Hashed cgMLST

open access: yesFrontiers in Microbiology, 2021
Whole-genome sequencing (WGS)-based outbreak investigation has proven to be a valuable method for the surveillance of bacterial pathogens. Its utility has been successfully demonstrated using both gene-by-gene (cgMLST or wgMLST) and single-nucleotide ...
Carlus Deneke   +4 more
doaj   +1 more source

Genomic epidemiology of Neisseria gonorrhoeae in Shenzhen, China, during 2019–2020: increased spread of ceftriaxone-resistant isolates brings insights for strengthening public health responses

open access: yesMicrobiology Spectrum, 2023
The antimicrobial resistance (AMR) in gonorrhea poses global threat of increasing public health concern. In response to this concern, molecular surveillance has been widely utilized to detail the changes in the evolution and distribution of Neisseria ...
Di Wang   +5 more
doaj   +1 more source

What Should Health Departments Do with HIV Sequence Data?

open access: yesViruses, 2020
Many countries and US states have mandatory statues that require reporting of HIV clinical data including genetic sequencing results to the public health departments.
Ethan Romero-Severson   +2 more
doaj   +1 more source

Multiplex PCR Assay for Clade Typing of Salmonella enterica Serovar Enteritidis

open access: yesMicrobiology Spectrum, 2022
Salmonella enterica serovar Enteritidis is one of the most commonly reported serovars of nontyphoidal Salmonella causing human disease and is responsible for both gastroenteritis and invasive nontyphoidal Salmonella (iNTS) disease worldwide. Whole-genome
Sarah Gallichan   +5 more
doaj   +1 more source

Plasmodium falciparum kelch 13 Mutations, 9 Countries in Africa, 2014–2018

open access: yesEmerging Infectious Diseases, 2021
The spread of drug resistance to antimalarial treatments poses a serious public health risk globally. To combat this risk, molecular surveillance of drug resistance is imperative.
Sarah E. Schmedes   +25 more
doaj   +1 more source

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