Results 131 to 140 of about 4,073,182 (253)

Programmable Encapsulation Enables On‐Demand Proliferation of Therapeutic Bacteria for Potent Cancer Immunotherapy

Advanced Science, EarlyView.
A programmable encapsulation technology is developed to reduce bacterial immunogenicity and proliferation after systemic administration. The cross‐linked polymer networks around individual bacteria enable immunogenic shielding and permit selective proliferation in tumors, allowing the bacteria to convert tumor‐accumulated ammonia into L‐arginine and ...
Jianhui Yang, Ao Peng, Shuaiqiang Li, Yaning Huang, Jian Yan, Leyuan Wang, Zhihui Zhu, Fei‐Long Liu, Erbao Bian, Yang Liu, Dasheng Tian, Fenghe Li, Qi Liu   +12 more
wiley   +1 more source

Molecular Surveillance Reveals Diverse Tick-Borne Pathogens in Northern California. [PDF]

Pathogens
Aboshi AR, Valencia R, Gomes BA, Sharma A, Rückert C, Teglas M, Nuss AB, Sarna-Wojcicki D, Saxon BJ, Tripp E, Camarena J, Tripp B, Gulia-Nuss M.   +12 more
europepmc   +1 more source

UCtracker: A Deep Learning–Based DNA Methylation Model for Noninvasive Diagnosis and Recurrence Surveillance of Urothelial Carcinoma in a Prospective Study

Advanced Science, EarlyView.
We developed UCtracker, a urine DNA methylation–based deep learning model, for noninvasive diagnosis and postoperative surveillance of urothelial carcinoma. UCtracker demonstrates high diagnostic accuracy, robustness at ultralow sequencing depth, early recurrence detection, and dynamic risk‐stratified monitoring of molecular residual disease ...
Shengwei Xiong, Gaojie Li, Yucai Wu, Yuan Liang, Heng Guo, Yu Zhang, Gengyan Xiong, Long Tian, Xin Zhang, Ye Tian, Zhengguo Ji, Bin Guo, Yue Shi, Jian Fan, Zhihua Li, Yanqing Gong, Shiming He, Xuesong Li, Weimin Ci, Liqun Zhou   +19 more
wiley   +1 more source

Molecular surveillance of multiplicity of infection, haplotype frequencies, and prevalence in infectious diseases. [PDF]

PLoS Comput Biol
Tsoungui Obama HCJ, Schneider KA.
europepmc   +1 more source

Nanovesicles With Mechanically Induced Adjuvanticity for Robust Melanoma Vaccination Toward Tumor‐Associated Macrophages

Advanced Science, EarlyView.
Rigidity‐tunable nanovesicle (P‐Pm) with mechanically induced adjuvanticity toward tumor‐associated macrophages (TAMs) was designed to engineer R848/gp100 antigen ‐loaded nanovaccine (P@Rg‐Pm), which achieved outstanding anti‐tumor outcomes in both therapeutic and preventive model of B16‐F10 melanoma.
Bangyue Luo, Liyan Qiu
wiley   +1 more source

Serological and Molecular Surveillance of Influenza A Virus in Dogs and Cats in Central Chile. [PDF]

Zoonoses Public Health
Baumberger C, Di Pillo F, Sanchez F, Sepúlveda A, Marambio V, Orozco K, Tapia D, Hamilton-West C, Sharp B, Schultz-Cherry S, Jiménez-Bluhm P.   +10 more
europepmc   +1 more source

Recursive Surveillance and the Persistence of Authoritarian Surveillance in Brazil

To comprehend contemporary surveillance in Brazil, especially under Bolsonaro’s administration (2019–2022), it is crucial to revisit the country’s most authoritarian period, the military dictatorship (1964–1985).
Melgaço, Lucas
core   +1 more source

Miro1 Protects Against Acute Kidney Injury Through Modulating Mitochondrial Homeostasis via Interaction With Sirt6

Advanced Science, EarlyView.
Ischemia‐reperfusion reduces Sirt6 activity, thereby increasing Miro1 acetylation. Hyperacetylated Miro1 exhibits perinuclear distribution and degradation, thereby inducing mitochondrial dysfunction and promoting apoptosis in renal tubular epithelial cells. This pathway reveals a mechanistic link between Sirt6‐mediated deacetylation and Miro1 stability
Lin Wu, Qing Li, Yiyang Xu, Zitao Wang, Hua Shu, Yangfan Wu, Fang Lu, Zhimin Huang, Bo Zhang, Hongwei Liang, Changying Xing, Huijuan Mao, Yanggang Yuan   +12 more
wiley   +1 more source

Editorial: Sequencing and phylogenetic analysis as a tool in molecular epidemiology of veterinary infectious diseases

Frontiers in Veterinary Science, 2023
Christina M. Leyson, Moh A. Alkhamis, Iryna V. Goraichuk, Iryna V. Goraichuk   +3 more
doaj   +1 more source

Molecular surveillance and genomic characterization of enterovirus D68 in southern Portugal, 2024-2025. [PDF]

Arch Virol
Santos-Silva S, Moreira G, Palma A, Rodrigues S, Simões M, Guerreiro R, Nascimento MSJ, Mesquita JR.   +7 more
europepmc   +1 more source