Results 141 to 150 of about 4,073,182 (253)

Chimeric IL‐6/4R‐LL37 Engineered Macrophages Achieve Synchronized Inflammation Control and Antimicrobial Defence in Sepsis

Advanced Science, EarlyView.
Engineered macrophages programmed in situ by LNP‐delivered IL‐6/4 fusion and LL37 mRNAs simultaneously dampen cytokine storm, promote M2‐like repair, and enhance direct bacterial killing in sepsis. This combinatorial strategy restores T cell and macrophage function, lowers organ bacterial burden, and improves survival, highlighting a precision, host ...
Tianyang Jie, Zheyu Zhang, Hao Zhang, Linke Bian, Penglong Zheng, Sijia Zhou, Minqi Wang, Mingyu Qu, Yufei Wang, Xinhua Qu, Bing Yue   +10 more
wiley   +1 more source

Local implementation of scalable malaria molecular surveillance in a low-resource setting: a North-South collaborative model. [PDF]

Malar J
Lukindu M, Lukyamuzi E, Ashraf F, Nagi SC, Ssekagiri A, Mugoya T, Yee C, Mukwaya S, Lucas E, Nolan T, Donnelly M, Kayondo J.   +11 more
europepmc   +1 more source

Protesters’ Reactions to Video Surveillance of Demonstrations: Counter-Moves, Security Cultures, and the Spiral of Surveillance and Counter-Surveillance

, 2018
This article analyses protesters’ reactions to police video surveillance of demonstrations in Germany. Theoretically, we draw on the concept of a “spiral of surveillance and counter-surveillance” to understand the interaction processes which ...
Knopp, Philipp, Ullrich, Peter
core  

circZNF148 Drives Glucose Metabolism Reprogramming to Enhance Metastasis and Immune Evasion via HK1 Stabilization in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
CircZNF148 stabilizes HK1 through deubiquitinase recruitment, thereby enhancing glycolysis and lactate production. Elevated lactate promotes PD‑L1 lactylation and membrane accumulation while suppressing CD8+ T‐cell cytotoxicity, collectively facilitating immune evasion and malignant progression in TNBC.
Yuhan Jin, Wenjing Zhao, Lei Wang, Jianing Wang, Keying Zhao, Dan Luo, Yifei Wang, Yuxia Yang, Jingze Yang, Yaming Li, Tong Chen, Dianwen Han, Zekun Wang, Xiaoyan Li, Bing Chen, Lijuan Wang, Yiran Liang, Qifeng Yang   +17 more
wiley   +1 more source

Seroprevalence and molecular surveillance of Dirofilaria immitis in shelter dogs from central New Mexico, USA. [PDF]

Parasit Vectors
Kelly MA, Starnes A, Schech M, Clarke E, Ramos RAN, Hakimi H, Weerarathne P, Verocai GG.   +7 more
europepmc   +1 more source

The Making of a Totalitarian Surveillance Machine: Surveillance in Turkey Under AKP Rule

, 2017
This article examines surveillance initiatives under the AKP rule in Turkey (2002-present). The AKP had first tested and perfected surveillance methods, including wiretapping, internet surveillance and surveillance by collaborator-informant networks ...
Topak, Ozgun
core  

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

MMS Américas: a regional network for malaria molecular surveillance. [PDF]

Malar J
MMS Américas Network.
europepmc   +1 more source

Weekly Report on Severe Acute Respiratory Infections (SARI), Ireland Week 4 2025 (week ending 26/01/2025)

Three sentinel hospital sites are now participating in the severe acute respiratory infections (SARI) surveillance programme in Ireland. Along with St Vincent’s University Hospital (SVUH) (commenced on 5th July 2021), both St James’s Hospital (SJH) and ...
Health Protection Surveillance Centre
core  

BraMARS: An Interpretable Histopathology‐Driven Deep Learning Model for Brain Metastasis Risk Stratification in Surgically Resected Limited‐Stage SCLC

Advanced Science, EarlyView.
This study presents BraMARS, an explainable deep learning model that estimates future brain metastasis risk in surgically resected limited‐stage small‐cell lung cancer using routine H&E‐stained whole‐slide images. By linking model‐attributed spatial histopathology with clinical outcomes and proteomic programs, BraMARS provides a biologically ...
Zijian Yang, Taolue Wang, Shilong Liu, Zicheng Zhang, Yibo Zhang, Fan Yang, Bo Yu, Shuaishuai Gao, Yu Chen, Lin Yang, Meng Zhou   +10 more
wiley   +1 more source