Results 91 to 100 of about 5,797,712 (321)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Viruses, 2015 Temperate bacteriophages possess a molecular switch, which regulates the lytic and lysogenic growth. The genomes of the temperate telomere phages N15, PY54 and ɸKO2 harbor a primary immunity region (immB) comprising genes for the prophage repressor, the ...
Jens Andre Hammerl +5 more
doaj +1 more source
Slow light in molecular aggregates nanofilms [PDF]
, 2011 We study slow light performance of molecular aggregates arranged in nanofilms by means of coherent population oscillations (CPO). The molecular cooperative behavior inside the aggregate enhances the delay of input signals in the GHz range in comparison ...
E. Cabrera-Granado +3 more
core +3 more sources
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
PLoS Pathogens, 2016 Herpesviruses persist indefinitely in their host through complex and poorly defined interactions that mediate latent, chronic or productive states of infection.
J. Buehler +9 more
semanticscholar +1 more source
Beilstein Journal of Organic Chemistry, 2019 In this work we apply a combination of steady state and time resolved luminescence and absorption spectroscopies to investigate the excited-state dynamics of a recently developed molecular photoswitch, belonging to the hydrazone family.
Alessandro Iagatti +5 more
doaj +1 more source
Reversible Red Fluorescent Molecular Switches
Angewandte Chemie International Edition, 2006 I see red, I see red, I see red: Optically switchable compounds were synthesized whose visible fluorescence can be quenched down to 6 % with light at 360–400 nm and then restored with red light from a diode laser. The molecular switch offers potential applications in data storage and far-field microscopy with spatial resolution far below the ...
Bossi, M. +3 more
openaire +4 more sources
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Evidence of a metabolic memory to early-life dietary restriction in male C57BL/6 mice [PDF]
, 2012 <p>Background: Dietary restriction (DR) extends lifespan and induces beneficial metabolic effects in many animals. What is far less clear is whether animals retain a metabolic memory to previous DR exposure, that is, can early-life DR preserve ...
A Ceriello +46 more
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source