Results 1 to 10 of about 208,473 (269)

Molecular Switches—Tools for Imparting Control in Drug Delivery Systems [PDF]

open access: yesFrontiers in Chemistry, 2022
Cancer is a globally prevalent cause of premature mortality. Of growing interest is the development of novel anticancer therapies and the optimisation of associated risks.
Owen Fitzmaurice   +2 more
doaj   +2 more sources

A massively parallel screening platform for converting aptamers into molecular switches [PDF]

open access: yesNature Communications, 2023
Aptamer-based molecular switches that undergo a binding-induced conformational change have proven valuable for a wide range of applications, such as imaging metabolites in cells, targeted drug delivery, and real-time detection of biomolecules.
Alex M. Yoshikawa   +7 more
doaj   +2 more sources

Recent Advances in Fuel‐Driven Molecular Switches and Machines [PDF]

open access: yesChemistryOpen, 2022
The molecular switches and machines arena has entered a new phase in which molecular machines operate under out‐of‐equilibrium conditions using appropriate fuel.
Renitta Benny   +3 more
doaj   +2 more sources

Synthetic molecular switches driven by DNA-modifying enzymes [PDF]

open access: yesNature Communications
Taking inspiration from natural systems, in which molecular switches are ubiquitous in the biochemistry regulatory network, we aim to design and construct synthetic molecular switches driven by DNA-modifying enzymes, such as DNA polymerase and nicking ...
Hong Kang, Yuexuan Yang, Bryan Wei
doaj   +2 more sources

MicroRNAs as Molecular Switches in Macrophage Activation [PDF]

open access: yesFrontiers in Immunology, 2019
The efficacy of macrophage- mediated inflammatory response relies on the coordinated expression of key factors, which expression is finely regulated at both transcriptional and post-transcriptional level. Several studies have provided compelling evidence
Graziella Curtale   +4 more
doaj   +2 more sources

Current-induced mechanical torque in chiral molecular rotors

open access: yesBeilstein Journal of Nanotechnology, 2023
There has been great endeavor to engineer molecular rotors operated by an electrical current. A frequently met operation principle is the transfer of angular momentum taken from the incident flux.
Richard Korytár, Ferdinand Evers
doaj   +1 more source

Computational design of metal-supported molecular switches: Transient ion formation during light- and electron-induced isomerisation of azobenzene [PDF]

open access: yes, 2018
In molecular nanotechnology, a single molecule is envisioned to act as the basic building block of electronic devices. Such devices may be of special interest for organic photovoltaics, data storage, and smart materials.
Maurer, Reinhard J., Reuter, Karsten
core   +3 more sources

Laser controlled molecular switches and transistors [PDF]

open access: yes, 2002
We investigate the possibility of optical current control through single molecules which are weakly coupled to leads. A master equation approach for the transport through a molecule is combined with a Floquet theory for the time-dependent molecule.
Aviram   +31 more
core   +2 more sources

Spiers Memorial Lecture: Molecular mechanics and molecular electronics [PDF]

open access: yes, 2006
We describe our research into building integrated molecular electronics circuitry for a diverse set of functions, and with a focus on the fundamental scientific issues that surround this project.
Beckman, Robert   +11 more
core   +1 more source

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