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Artificial molecular motors in biological applications [PDF]
Frontiers in Molecular BiosciencesMolecular motors are the cornerstone for the maintenance of living systems and mediate almost all fundamental processes involved in cellular trafficking.
Fuli Fan +4 more
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Nature, 2023 AbstractMacroscopic electric motors continue to have a large impact on almost every aspect of modern society. Consequently, the effort towards developing molecular motors1–3 that can be driven by electricity could not be more timely. Here we describe an electric molecular motor based on a [3]catenane4,5, in which two cyclobis(paraquat-p-phenylene)6 ...
Raymond Dean Astumian +2 more
exaly +8 more sources
Exploring molecular motors [PDF]
Materials Chemistry Frontiers, 2021 The introduction of mechanical functions and controlled motion based on molecular motors and machines offers tremendous opportunities towards the design of dynamic molecular systems and responsive materials.
Jos C. M. Kistemaker +2 more
openaire +5 more sources
Nuclear deformation by microtubule molecular motors. [PDF]
PLoS Computational BiologyWe present a model to calculate the displacement and extension of deformable cellular cargo pulled by molecular motors stepping along cytoskeletal filaments.
Naruemon Rueangkham +3 more
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Photo-responsive functional materials based on light-driven molecular motors [PDF]
Light: Science & ApplicationsIn the past two decades, the research and development of light-triggered molecular machines have mainly focused on developing molecular devices at the nanoscale.
Yanping Deng +6 more
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Molecular Motors Orchestrate Pause-and-Run Dynamics to Facilitate Intracellular Transport [PDF]
BiomoleculesIntracellular transport is essential for cellular organization and function. This process is driven by molecular motors that ferry cargo along microtubules, but is characterized by intermittent motility, where cargoes switch between directed runs and ...
Yusheng Shen, Kassandra M. Ori-McKenney
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All-visible-light-driven salicylidene schiff-base-functionalized artificial molecular motors [PDF]
Nature CommunicationsLight-driven rotary molecular motors are among the most promising classes of responsive molecular machines and take advantage of their intrinsic chirality which governs unidirectional rotation.
Sven van Vliet +3 more
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The classification and therapeutic applications of molecular motors
European Journal of Medicinal Chemistry Reports, 2021 The molecular motors are protein molecules which can be teamed up to form the active mobile nanomachine with special functions. As a new type of therapeutic target different from normal enzymes or receptors, molecular motor plays a unique role in the ...
Mingyuan Li +10 more
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A new perspective on microtubule dynamics: destruction by molecular motors and self-repair
Comptes Rendus Biologies, 2021 Microtubules are dynamic polymers, permanently assembling and disassembling, that serve as tracks for intra-cellular transport by molecular motors. We recently found that the low energy of tubulin dimer interactions allows for spontaneous loss of tubulin
Triclin, Sarah +4 more
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Solvation Effects on the Thermal Helix Inversion of Molecular Motors from QM/MM Calculations
Chemistry, 2022 Molecular motors convert light and thermal energies into mechanical work, offering good opportunities to design novel molecular devices. Among them, molecular motors alternate a photoisomerization and a thermal helix inversion to achieve unidirectional ...
Jin Wen, Meifang Zhu, Leticia González
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