Results 1 to 10 of about 215,535 (300)

Measuring and modeling polymer gradients argues that spindle microtubules regulate their own nucleation

open access: yesNew Journal of Physics, 2017
Spindles are self-organized microtubule-based structures that segregate chromosomes during cell division. The mass of the spindle is controlled by the balance between microtubule turnover and nucleation. The mechanisms that control the spatial regulation
Foster, Peter J.   +5 more
core   +2 more sources

Sulfo-SMCC Prevents Annealing of Taxol-Stabilized Microtubules In Vitro [PDF]

open access: yesPLoS ONE, 2016
Microtubule structure and functions have been widely studied in vitro and in cells. Research has shown that cysteines on tubulin play a crucial role in the polymerization of microtubules.
Prabhune, Meenakshi   +3 more
core   +4 more sources

Ectopic A-lattice seams destabilize microtubules [PDF]

open access: yes, 2014
Natural microtubules typically include one A-lattice seam within an otherwise helically symmetric B-lattice tube. It is currently unclear how A-lattice seams influence microtubule dynamic instability.
A des Georges   +54 more
core   +1 more source

Microtubule dynamics depart from wormlike chain model [PDF]

open access: yes, 2007
Thermal shape fluctuations of grafted microtubules were studied using high resolution particle tracking of attached fluorescent beads. First mode relaxation times were extracted from the mean square displacement in the transverse coordinate.
Ernst-Ludwig Florin   +5 more
core   +2 more sources

Microtubules in Bacteria: Ancient Tubulins Build a Five-Protofilament Homolog of the Eukaryotic Cytoskeleton [PDF]

open access: yes, 2011
Microtubules play crucial roles in cytokinesis, transport, and motility, and are therefore superb targets for anti-cancer drugs. All tubulins evolved from a common ancestor they share with the distantly related bacterial cell division protein FtsZ, but ...
A Briegel   +66 more
core   +5 more sources

Mammalian kinetochores count attached microtubules in a sensitive and switch-like manner. [PDF]

open access: yes, 2019
The spindle assembly checkpoint (SAC) prevents anaphase until all kinetochores attach to the spindle. Each mammalian kinetochore binds many microtubules, but how many attached microtubules are required to turn off the checkpoint, and how the kinetochore ...
Akiyoshi   +80 more
core   +1 more source

Chlamydia Hijacks ARF GTPases To Coordinate Microtubule Posttranslational Modifications and Golgi Complex Positioning. [PDF]

open access: yes, 2017
The intracellular bacterium Chlamydia trachomatis develops in a parasitic compartment called the inclusion. Posttranslationally modified microtubules encase the inclusion, controlling the positioning of Golgi complex fragments around the inclusion.
Agata Nawrotek   +10 more
core   +3 more sources

Effects of antibodies against dynein and tubulin on the stiffness of flagellar axonemes [PDF]

open access: yes, 1981
Antidynein antibodies, previously shown to inhibit flagellar oscillation and active sliding of axonemal microtubules, increase the bending resistance of axonemes measured under relaxing conditions, but not the bending resistance of axonemes measured ...
Asai, D. J.   +3 more
core   +1 more source

Tubulins in C. elegans [PDF]

open access: yes, 2018
The C. elegans tubulin family is composed of nine α-, six β-, and one γ-tubulin. Tubulins are highly conserved, functioning as α-β heterodimers that assemble into microtubules.
Hurd, Daryl D.
core   +2 more sources

Prime movers : mechanochemistry of mitotic kinesins [PDF]

open access: yes, 2014
Mitotic spindles are self-organizing protein machines that harness teams of multiple force generators to drive chromosome segregation. Kinesins are key members of these force-generating teams.
A Blangy   +184 more
core   +1 more source

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