The emerging role of microtubules in invasion plasticity
The ability of cells to switch between different invasive modes during metastasis, also known as invasion plasticity, is an important characteristic of tumor cells that makes them able to resist treatment targeted to a particular invasion mode.
Anna Legátová +9 more
doaj +1 more source
A "MICROTUBULE" IN A BACTERIUM [PDF]
A study of the anchorage of the flagella in swarmers of Proteus mirabilis led to the incidental observation of microtubules. These microtubules were found in thin sections and in whole mount preparations of cells from which most of the content had been released by osmotic shock before staining negatively with potassium phosphotungstate (PTA).
W, van Iterson +2 more
openaire +2 more sources
Studies on the interaction between "Tobacco Mosaic Virus" movement protein and microtubules [PDF]
During the invasion of a susceptible host, Tobacco mosaic virus (TMV) transports its RNA genome from sites of viral synthesis into neighbouring cells, thus potentiating the spread of infection.
Ashby, Jamie A.
core +1 more source
Functional coupling of microtubules to membranes - implications for membrane structure and dynamics [PDF]
The microtubule network dictates much of the spatial patterning of the cytoplasm, and the coupling of microtubules to membranes controls the structure and positioning of organelles and directs membrane trafficking between them.
Stephens, David J
core +1 more source
CLASP promotes microtubule bundling in metaphase spindle independently of Ase1/PRC1 in fission yeast
Microtubules in the mitotic spindle are organised by microtubule-associated proteins. In the late stage of mitosis, spindle microtubules are robustly organised through bundling by the antiparallel microtubule bundler Ase1/PRC1. In early mitosis, however,
Hirohisa Ebina, Liang Ji, Masamitsu Sato
doaj +1 more source
TACC3-ch-TOG track the growing tips of microtubules independently of clathrin and Aurora-A phosphorylation [PDF]
The interaction between TACC3 (transforming acidic coiled coil protein 3) and the microtubule polymerase ch-TOG (colonic, hepatic tumor overexpressed gene) is evolutionarily conserved.
Cristina Gutiérrez-Caballero +11 more
core +1 more source
Kinesin-propelled label-free microtubules imaged with interference reflection microscopy
Interference reflection microscopy (IRM) utilizes the interference between the light reflected from the surface and the light reflected from an object to generate contrast and can be used to image nanometer size objects, such as a microtubule adhered to ...
Gadiel Saper, Henry Hess
doaj +1 more source
Cell proliferation, cell shape, and microtubule and cellulose microfibril organization of tobacco BY-2 cells are not altered by exposure to near weightlessness in space [PDF]
The microtubule cytoskeleton and the cell wall both play key roles in plant cell growth and division, determining the plant’s final stature. At near weightlessness, tubulin polymerizes into microtubules in vitro, but these microtubules do not self ...
Emons, A.M.C. +13 more
core +1 more source
Microtubules (MTs) are highly conserved polar polymers that are key elements of the eukaryotic cytoskeleton and are essential for various cell functions. αβ-tubulin, a heterodimer containing one structural GTP and one hydrolysable and exchangeable GTP, is the building block of MTs and is formed by the sequential action of several molecular chaperones ...
openaire +2 more sources
Surface topography of microtubule walls decorated with monomeric and dimeric kinesin constructs [PDF]
The surface topography of opened-up microtubule walls (sheets) decorated with monomeric and dimeric kinesin motor domains was investigated by freeze-drying and unidirectional metal shadowing.
Mandelkow, Eckhard +13 more
core +2 more sources

