Results 191 to 200 of about 2,123,606 (402)

AI-Driven Hybrid Ecological Model for Predicting Oncolytic Viral Therapy Dynamics [PDF]

arXiv
Oncolytic viral therapy (OVT) is an emerging precision therapy for aggressive and recurrent cancers. However, its clinical efficacy is hindered by the complexity of tumor-virus-immune interactions and the lack of predictive models for personalized treatment.
arxiv  

Feasibility of a deep-inspiration breath-hold [18F]AlF-NOTA-LM3 PET/CT imaging on upper-abdominal lesions in NET patients: in comparison with respiratory-gated PET/CT

EJNMMI Physics
Purposes To explore the clinical feasibility and efficacy of a deep inspiration breath-hold (BH) PET/CT using [18F]AlF-NOTA-LM3 on upper abdominal lesions in patients with neuroendocrine tumors (NETs).
Haiqiong Zhang, Meixi Liu, Ximin Shi, Jiangyu Ma, Chao Ren, Zhenghai Huang, Ying Wang, Hongli Jing, Li Huo   +8 more
doaj   +1 more source

Combining Radiation and Molecular Targeting in Cancer Therapy [PDF]

, 2004
Kenneth D. Tew
openalex   +1 more source

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

Molecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou, Aliki Ntzifa, Victoria Tserpeli, Ioanna Balgkouranidou, Alkistis Papatheodoridi, Evangelia Razis, Helena Linardou, Christos Papadimitriou, Amanda Psyrri, Flora Zagouri, Stylianos Kakolyris, Evi Lianidou   +11 more
wiley   +1 more source

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

Molecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu, Fenglin Shen, Yang Liu, Ziqing Zhong, Yongling Chen, Zhiyuan Xia, Cuiju Mo, Hongxiu Yu   +7 more
wiley   +1 more source

Development of a biomimetic nanoparticle platform for apigenin therapy in triple-negative breast cancer

Frontiers in Oncology
BackgroundThis study investigates the therapeutic potential and mechanisms of Apigenin (AGN) in treating triple-negative breast cancer (TNBC). Although AGN is recognized for its anti-tumor properties, its specific mechanisms in TNBC remain unclear ...
Chenyang Wang, Chenyang Wang, Chenyang Wang, Xiaojing Ren, Xiaojing Ren, Xiaojing Ren, Yanmei Han, Yanmei Han, Yanmei Han, Ding Nan, Ding Nan, Ding Nan, Yajing Zhang, Yajing Zhang, Yajing Zhang, Zairong Gao, Zairong Gao, Zairong Gao   +17 more
doaj   +1 more source

Conversion therapy for advanced cholangiocarcinoma in the era of molecular targeted therapy and immune therapy. [PDF]

Hepatobiliary Surg Nutr, 2023
Zhang Z, Zhang W.
europepmc   +1 more source

Cholangiocarcinoma: Molecular targeting strategies for chemoprevention and therapy [PDF]

, 2004
Alphonse E. Sirica
openalex   +1 more source

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

Molecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy, Heather Fairfield, Victoria E. DeMambro, Samaa Fadel, Carlos A. Gartner, Michelle Karam, Christian Potts, Princess Rodriguez, Ya‐Wei Qiang, Habib Hamidi, Xiangnan Guan, Calvin P. H. Vary, Michaela R. Reagan   +12 more
wiley   +1 more source

Role of Toll-Like Receptors in the interplay between pathogen and damage associated molecular patterns [PDF]

arXiv, 2019
Various theoretical studies have been carried out to infer relevant protein-protein interactions among pathogens and their hosts. Such studies are generally based on preferential attachment of bacteria / virus to their human receptor homologs. We have analyzed 17 pathogenic species mainly belonging to bacterial and viral pathogenic classes, with the ...
arxiv